Results 21 to 30 of about 263,159 (256)
Frontiers in Oncology, 2018 Purpose/Objective: High-grade glioma is the most common primary malignant tumor of the CNS, with death often resulting from uncontrollable intracranial disease.
Michael C. Repka +11 more
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Pathogenesis Study of Glioma: From Glioma Stem Cells, Genomic Tags, to Rodent Models [PDF]
, 2023 Despite the past two decades of research progress, glioma still remains the most challenging of all primary central nervous system (CNS) tumors. The complexity of its pathogenesis makes the disease hard to deal with, especially glioblastoma multiforme ...
core +1 more source
The Turkish Journal of Pediatrics, 2016 The methylenetetrahydrofolate reductase (MTHFR) gene plays a key role in carcinogenesis through its effects on DNA synthesis and methylation and also has a significant role in the etiology of many disorders, such as diabetes, migraine, and ...
Hikmet Gülşah Tanyıldız +7 more
doaj +1 more source
Brain Sciences, 2023 The sphenoid ridge approach (SRA) was initially described as a surgical technique for treating vascular pathologies near the Sylvian fissure. However, limited studies have systematically explored the use of skull base techniques in pediatric patients ...
Roberto Garcia-Navarrete +3 more
doaj +1 more source
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy [PDF]
, 2011 Background: Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect.
Stefan Walenta +26 more
core +2 more sources
PEDIATRIC OPTIC PATHWAY GLIOMA: DIENCEPHALIC SYNDROME
Сибирский онкологический журнал, 2021 Diencephalic cachexia (DC ) is a metabolic disorder characterized by a decrease in body weight. DC usually occurs in the presence of glioma brain tumors extended into the optic pathway.
A. F. Valiakhmetova +12 more
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Frontiers in Neurology, 2020 Approximately 20% of patients with Neurofibromatosis type 1 (NF1) develop optic pathway gliomas (OPGs). Not all OPGs in NF1 necessarily become vision compromising and predicting which patients might develop visual decline is difficult at present time ...
Amirah I. Momen +5 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
A rare case of large bilateral optic nerve glioma in a child without neurofibromatosis type 1
Kerala Journal of Ophthalmology, 2016 We report a rare case of atypical large bilateral malignant optic nerve glioma in a child with no clinical evidence of neurofibromatosis.
Virna M Shah, Sukumar Sharanya
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Cell Transplantation, 2020 The optic pathway glioma (OPG) is a slow-growing brain tumor that arises along the optic nerve or its downstream connections and causing vision to gradually worsen with time.
Deepti Singh +4 more
doaj +1 more source