Results 141 to 150 of about 263,159 (256)

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Deep‐Learning Based Contrast Boosting: A Multi‐Center Multi‐Reader Study on Clinical Performance With Standard Contrast Enhanced Brain MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Gadolinium‐based contrast agents are used in brain MRI to improve the visualization of disorders and improve the delineation of lesions. Higher doses of GBCAs can improve lesion sensitivity but may have safety implications, particularly in light of recent findings on gadolinium retention and deposition.
Srivathsa Pasumarthi Venkata   +10 more
wiley   +1 more source

Functional Imaging for Identification of Functionally Critical Brain Regions to Spare in Glioma Radiation Therapy Planning: A Systematic Review

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This review highlights the role of functional imaging in sparing cognitive brain regions during glioma radiotherapy. It shows promising dose reduction without compromising target coverage, but evidence remains limited, requiring standardisation and prospective validation.
Li Wen Yeo, John T. Ryan
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Oligodendrocytoma of the Optic Nerve, Report of a Case

open access: yesActa Medica Iranica, 1963
The case under consideration was a glioma of the optic nerve, one of the rarer tumors. Microscopically it was diagnosed as a oligodendrocytoma. The patient, whose disease bage before the age of puberty, complain.ed of poor vision which in the course of ...
A. M. Zia Shamsa, M. H. Lashkari
doaj  

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti   +6 more
wiley   +1 more source

Iterative Navigator‐Based Retrospective Motion Correction for Multi‐Shot Brain MR Elastography and Evaluation of Single‐Shot Post‐Reconstruction Correction

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Brain MR elastography (MRE) is uniquely sensitive to subject motion, as even small phase deviations can produce large errors in the mechanical properties estimated. Existing motion correction strategies have not been validated for MRE and are often incompatible with complex multi‐shot or joint temporal reconstructions.
Zhuoyu Shi   +2 more
wiley   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

open access: yesPediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu   +5 more
wiley   +1 more source

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