Results 161 to 170 of about 263,159 (256)

Head-to-head preclinical treatment design prioritizes promising therapies for neurofibromatosis type 1 optic glioma clinical translation. [PDF]

Neurooncol Adv
Eligator T, Chatterjee J, Yamada S, Kirchner A, Nair HB, Fangusaro JR, Gutmann DH.   +6 more
europepmc   +1 more source

Advances in deep‐tissue fluorescence imaging through optical clearing: A review

VIEW, EarlyView.
Optical clearing refers to techniques that are used to improve the optical transparency of biological tissues. Optical clearing enables imaging of deeper lying tissues as well as 3D volumetric imaging of whole organs. This review examines reports on the integration of optical clearing with advanced fluorescence imaging techniques, with particular ...
Alaka Pramod, Sanoop Pavithran M, Valery V. Tuchin, Santhosh Chidangil, C. S. Suchand Sandeep   +4 more
wiley   +1 more source

NF1 mutation-driven neuronal hyperexcitability sets a threshold for tumorigenesis and therapeutic targeting of murine optic glioma. [PDF]

Neuro Oncol
Anastasaki C, Chatterjee J, Koleske JP, Gao Y, Bozeman SL, Kernan CM, Marco Y Marquez LI, Chen JK, Kelly CE, Blair CJ, Dietzen DJ, Kesterson RA, Gutmann DH.   +12 more
europepmc   +1 more source

AML‐Net: Attention‐based multi‐scale lightweight model for brain tumour segmentation in internet of medical things

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Brain tumour segmentation employing MRI images is important for disease diagnosis, monitoring, and treatment planning. Till now, many encoder‐decoder architectures have been developed for this purpose, with U‐Net being the most extensively utilised. However, these architectures require a lot of parameters to train and have a semantic gap. Some
Muhammad Zeeshan Aslam, Basit Raza, Muhammad Faheem, Aadil Raza   +3 more
wiley   +1 more source

Estrogen-induced glial IL-1β mediates extrinsic retinal ganglion cell vulnerability in murine Nf1 optic glioma. [PDF]

Ann Clin Transl Neurol
Tang Y, Chatterjee J, Wagoner N, Bozeman S, Gutmann DH.   +4 more
europepmc   +1 more source

Non-optic glioma in adults and children with neurofibromatosis 1. [PDF]

Orphanet J Rare Dis, 2017
Sellmer L, Farschtschi S, Marangoni M, Heran MK, Birch P, Wenzel R, Friedman JM, Mautner VF.   +7 more
europepmc   +1 more source

Dissecting Glioma Heterogeneity: A Deep Hybrid Graph Convolutional Network With Hinge Attention for Causal‐Effect Explainability

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Brain tumour classification is a critical task in medical imaging that requires accurate and interpretable solutions to assist in clinical decision‐making. In this paper, we present GraphConvNet‐X, a novel hybrid model that integrates convolutional neural networks (CNNs) for spatial feature extraction with graph neural networks (GNNs) that ...
Sultanul Arifeen Hamim, Mubasshar U. I. Tamim, S. M. Hasan Mahmud, M. F. Mridha, Zeyar Aung   +4 more
wiley   +1 more source

Copy number variation analysis of cerebrospinal fluid metagenomic next‐generation sequencing data in assisting the diagnosis of pediatric brain tumors

Pediatric Investigation, EarlyView.
Changhong Ren, Xiuwei Zhuo, Xinying Yang, Xingfeng Yao, Shuai Gong, Hui Xiong, Fang Fang, Weihua Zhang   +7 more
wiley   +1 more source

Clinical evaluation of the CrossNN DNA methylation classifier for central nervous system tumors

Brain Pathology, EarlyView.
CrossNN demonstrated non‐inferiority to the Heidelberg CNS Tumor Methylation Classifier. A dual‐classifier approach increased the number of clinically informative classifications with correct tumor type assignment while maintaining a low rate of incorrect predictions.
Jonas Dahnoun, Léon C. van Kempen, Senada Koljenović, Ken Op de Beeck, Tomas Menovsky, Bart Feyen, Melek Ahmed, Anne Sieben, Karen Zwaenepoel   +8 more
wiley   +1 more source

PTEN homozygous deletion is a negative prognostic factor in tumor treating fields‐treated glioblastoma, IDH wildtype patients

Brain Pathology, EarlyView.
In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles, Claudius Jelgersma, Christin Siewert, Brendan Osberg, Simone Schmid, Arend Koch, Eilís Perez, Daniel Teichmann, Martin Misch, Anna‐Gila Karbe, Susanne Ukrow, Patrick N. Harter, Ruth M. Stassart, Peter Vajkoczy, Julia Onken, David Capper   +15 more
wiley   +1 more source