Results 81 to 90 of about 263,159 (256)

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

open access: yesAdvanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang   +20 more
wiley   +1 more source

Clinical and Treatment Features of Orbital Neurogenic Tumors

open access: yesTürk Oftalmoloji Dergisi, 2013
Purpose: To evaluate the clinical and treatment features of orbital neurogenic tumors. Material and Method: The records of 35 patients with orbital neurogenic tumors who were diagnosed and treated at Ankara University Faculty of Medicine, Department of
Pınar Bingöl Kızıltunç   +2 more
doaj   +1 more source

Hypoxia helps glioma to fight therapy [PDF]

open access: yes, 2009
Despite major improvements in the surgical management the prognosis for patients bearing malignant gliomas is still dismal. Malignant gliomas are notoriously resistant to treatment and the survival time of patients is between 3-8 years for low-grade and
Amberger-Murphy, Verena   +1 more
core   +2 more sources

Ciliary Membrane Lipid Homeostasis in Health and Disease

open access: yesAdvanced Science, EarlyView.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang   +3 more
wiley   +1 more source

F2b09 Optic Disc Swelling from Malignant Optic Nerve Glioma

open access: yes, 1971
Malignant optic nerve glioma of adulthood with blindness and optic disc edema. Right image shows white material extruded from the swollen optic disc. This material is myelin being squeezed into the eye from the nerve infarction.
William F. Hoyt, MD
core  

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

open access: yesAdvanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Applied Fiber Optic Measurement for Geohydraulic Engineering [PDF]

open access: yes, 1997
Engineers have long sought the possibility of measuring parameters such as temperature and pressure continuously in the underground with high precision, high spatial resolution and high band width of parameters. Distributed fibre optic measurement offers
Nishigaki, Makoto, Schreck, Martin
core   +1 more source

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

open access: yesAdvanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee   +5 more
wiley   +1 more source

Intraorbital ancient pilocytic astrocytoma of the optic nerve in neurofibromatosis type 1 patient presenting with sudden ocular pain

open access: yesSAGE Open Medical Case Reports, 2018
Optic nerve pilocytic astrocytoma is an uncommon but well-known entity; however, intraorbital ancient pilocytic astrocytoma of the optic nerve is extremely rarely reported.
Haesu Lee Motoyama   +4 more
doaj   +1 more source

F2b03 Progressive Optic Disc Swelling with Optic Glioma

open access: yes, 1969
Progressive optic disc swelling with optic glioma. Left eye. Woman with optic disc swelling. Edema is becoming pale. May 1969. Same patient as F2b_02 and F2b_04. Anatomy: Optic disc.
William F. Hoyt, MD
core  

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