Results 11 to 20 of about 623,254 (248)

Bilateral Optic Nerve Atrophy Case Report [PDF]

Majalah Kedokteran Bandung
Wolfram syndrome, also known as DIDMOAD or juvenile onset diabetes mellitus, optic nerve atrophy, diabetes insipidus, and deafness, is a genetic neurological condition.
Mohammed R. Naqeeb, Dina M Abdulmannan
doaj   +4 more sources

Histopathology of optic nerve pit-associated maculopathy

Clinical Ophthalmology, 2012
John B Christoforidis, William Terrell, Frederick H DavidorfCollege of Medicine, The Ohio State University, Columbus, OH, USAPurpose: To describe the histopathologic findings of an eye bank specimen containing an optic nerve pit with associated serous ...
Christoforidis JB, Terrell W, Davidorf FH   +2 more
doaj   +1 more source

Development of a novel model of optic neuritis to assess neuroprotective and repair strategies in multiple sclerosis [PDF]

, 2012
PhDMultiple sclerosis (MS) is a putative autoimmune disease of the central nervous system (CNS), which often affects the optic nerve pathway. Optic neuritis (ON) is a clinical feature of MS that can cause loss of vision due to conduction block and ...
Lidster, Katie
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Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy [PDF]

, 2010
Background: Up to the 1950s, there was an ongoing debate about the diversity of hereditary optic neuropathies, in particular as to whether all inherited optic atrophies can be ascribed to Leber's hereditary optic neuropathy (LHON) or represent different ...
Alexander Christiane, Schimpf Simone, Bernd Wissinger, Zrenner, Eberhart, Alavi, M.V., Schimpf, Simone, Auburger Georg, Zrenner, E., Zrenner Eberhart, Schimpf, S., Alavi-Khorassani Moghadam, Marcel Victor, Auburger, Georg, Leo-Kottler, Beate, Marcel V Alavi, Wissinger, Bernd, Christiane Alexander, Nico Fuhrmann, Wissinger, B., Fuhrmann Nico, Beate Leo-Kottler, Alexander, Christiane, Kamenisch, York, Fuhrmann, Nico, Kamenisch, Y., Wissinger Bernd, Auburger, G., Simone Schimpf, Eberhart Zrenner, Georg Auburger, Kamenisch York, York Kamenisch, Alexander, C., Leo-Kottler, B., Leo-Kottler Beate, Alavi Marcel V, Fuhrmann, N.   +35 more
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Wolfram syndrome with childhood glaucoma: A rare case report with review of literature

Journal of Clinical Ophthalmology and Research, 2020
Wolfram syndrome (WFS) is a rare neurodegenerative disorder characterized by young-onset diabetes mellitus, central diabetes insipidus, optic nerve atrophy, and hearing loss.
Divya Kesarwani, Gunjan Jain, Sarswati, Rachna Agarwal, Kumudini Sharma, Vaibhav Kumar Jain   +5 more
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Mouse Nr2f1 haploinsufficiency unveils new pathological mechanisms of a human optic atrophy syndrome

EMBO Molecular Medicine, 2019
Optic nerve atrophy represents the most common form of hereditary optic neuropathies leading to vision impairment. The recently described Bosch‐Boonstra‐Schaaf optic atrophy (BBSOA) syndrome denotes an autosomal dominant genetic form of neuropathy caused
Michele Bertacchi, Agnès Gruart, Polynikis Kaimakis, Cécile Allet, Linda Serra, Paolo Giacobini, José M Delgado‐García, Paola Bovolenta, Michèle Studer   +8 more
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Etiology and clinical profile of childhood optic nerve atrophy at a tertiary eye care center in South India

Indian Journal of Ophthalmology, 2014
Background: Optic nerve atrophy is an important ophthalmological sign that may be associated with serious systemic conditions having a significant bearing on the overall morbidity of the child.
Supriya Chinta, Batriti S Wallang, Virender Sachdeva, Amit Gupta, Preeti Patil-Chhablani, Ramesh Kekunnaya   +5 more
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Nogo receptor 1 is expressed by nearly all retinal ganglion cells. [PDF]

PLoS ONE, 2018
A variety of conditions ranging from glaucoma to blunt force trauma lead to optic nerve atrophy. Identifying signaling pathways for stimulating axon growth in the optic nerve may lead to treatments for these pathologies.
Alexander M Solomon, Teleza Westbrook, Greg D Field, Aaron W McGee   +3 more
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Neuro-ophthalmic manifestations of central nervous system tuberculosis: Compilation of three diverse unique presentations

Kerala Journal of Ophthalmology, 2022
Tubercular meningitis is the most devastating form of tuberculosis. Neuro-ophthalmic involvement can manifest as cranial nerve palsies, pupil abnormalities, disc changes, like papillitis, papilloedema, or optic atrophy and choroidal tubercles.
Harsha Sammer Pagad, Rishwa Hariyani, Akash Jain, Nita Shanbhag   +3 more
doaj   +1 more source

TGF-beta(2)- and H2O2-Induced Biological Changes in Optic Nerve Head Astrocytes Are Reduced by the Antioxidant Alpha-Lipoic Acid [PDF]

, 2012
Background/Aims: The goal of the present study was to determine whether transforming growth factor-beta(2) (TGF-beta(2))- and oxidative stress-induced cellular changes in cultured human optic nerve head (ONH) astrocytes could be reduced by pretreatment ...
Yu, Alice L., Welge-Lussen, Ulrich, Moriniere, Jerome   +2 more
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