Morning Glory Disc Anomaly, A Report of a Successfully Treated Case of Functional Amblyopia [PDF]
Journal of Clinical and Diagnostic Research, 2015 Morning Glory Disc Anomaly (MGDA) is a congenital malformation of the optic nerve characterized by the presence of a funnel-shaped macropapilla with neuroglial remnants in its center surrounded by an elevated and pigmented chorioretinal ring.
Humberto Cavazos-Adame +3 more
doaj +1 more source
Photopic negative response recorded with RETeval system in eyes with optic nerve disorders
Scientific Reports, 2022 Electroretinography (ERG) is used to evaluate the physiological status of the retina and optic nerve. The purpose of this study was to determine the usefulness of ERGs recorded with the RETeval system in diagnosing optic nerve diseases.
Tsutomu Yamashita +7 more
doaj +1 more source
Medical management of hereditary optic neuropathies. [PDF]
, 2014 Hereditary optic neuropathies are diseases affecting the optic nerve. The most common are mitochondrial hereditary optic neuropathies, i.e., the maternally inherited Leber's hereditary optic neuropathy (LHON) and dominant optic atrophy (DOA).
Barboni, Piero +4 more
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α-Synuclein pathology in post-mortem retina and optic nerve is specific for α-synucleinopathies
npj Parkinson's Disease, 2023 There is increasing interest in studying retinal biomarkers for various neurodegenerative diseases. Specific protein aggregates associated with neurodegenerative diseases are present in the retina and could be visualised in a non-invasive way. This study
Frederique J. Hart de Ruyter +10 more
doaj +1 more source
Gene therapy for optic nerve disease [PDF]
Eye, 2004 There has been recent interest in the potential use of gene therapy techniques to treat ocular disease. In this article, we consider the optic nerve diseases that are potentially most amenable to gene therapy.We discuss the recent success of gene transfer experiments in animal models of glaucoma, optic neuritis, Leber's hereditary optic neuropathy ...
K R G, Martin, H A, Quigley
openaire +2 more sources
Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]
, 2019 As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick +2 more
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Prediction of the course of primary open-angle glaucoma in combination with diabetic retinopathy using a mathematical model [PDF]
E3S Web of Conferences, 2020 It is possible to accurately diagnose diseases in the early stages using optical coherence tomography. A mathematical model has been developed for two diseases: glaucoma and diabetic retinopathy.
Vorobyeva I V
doaj +1 more source
Optic nerve head segmentation [PDF]
, 2004 Reliable and efficient optic disk localization and segmentation are important tasks in automated retinal screening. General-purpose edge detection algorithms often fail to segment the optic disk due to fuzzy boundaries, inconsistent image contrast or ...
Basu, A. +6 more
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Progressive ataxia with oculo-palatal tremor and optic atrophy [PDF]
, 2013 The final publication is available at Springer via doi: 10.1007/s00415-013-7136-
A. M. Bronstein +17 more
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TGF-beta(2)- and H2O2-Induced Biological Changes in Optic Nerve Head Astrocytes Are Reduced by the Antioxidant Alpha-Lipoic Acid [PDF]
, 2012 Background/Aims: The goal of the present study was to determine whether transforming growth factor-beta(2) (TGF-beta(2))- and oxidative stress-induced cellular changes in cultured human optic nerve head (ONH) astrocytes could be reduced by pretreatment ...
Abdul HM +60 more
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