Results 41 to 50 of about 135,611 (344)
Background The following study investigates the involvement of optic neuropathy in IgG4-related ophthalmic diseases (IgG4-ROD) based on the magnetic resonance imaging (MRI) data, and different imaging features of IgG4-ROD related optic neuropathy related
Jing Li +5 more
doaj +1 more source
Role of Oxidative Stress in Ocular Diseases Associated with Retinal Ganglion Cells Degeneration
Ocular diseases associated with retinal ganglion cell (RGC) degeneration is the most common neurodegenerative disorder that causes irreversible blindness worldwide. It is characterized by visual field defects and progressive optic nerve atrophy.
Eugene Yu-Chuan Kang +6 more
doaj +1 more source
Gene therapy for optic nerve disease [PDF]
There has been recent interest in the potential use of gene therapy techniques to treat ocular disease. In this article, we consider the optic nerve diseases that are potentially most amenable to gene therapy.We discuss the recent success of gene transfer experiments in animal models of glaucoma, optic neuritis, Leber's hereditary optic neuropathy ...
K R G, Martin, H A, Quigley
openaire +2 more sources
Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio +6 more
core +1 more source
IntroductionOptic neuropathy is an affection of the optic neurons, which ends with blindness and occurs either primarily due to direct affection of the optic nerve or secondarily as a complication of chronic diseases and/or adverse effects of their ...
Amira Ebrahim Alsemeh +10 more
doaj +1 more source
Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always [PDF]
Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs deputed to non-image forming functions of the eye such as synchronization of circadian rhythms to light-dark cycle.
Carelli, Valerio +7 more
core +1 more source
Automated Fovea Detection Based on Unsupervised Retinal Vessel Segmentation Method [PDF]
The Computer Assisted Diagnosis systems could save workloads and give objective diagnostic to ophthalmologists. At first level of automated screening of systems feature extraction is the fundamental step. One of these retinal features is the fovea.
Kalantari, Faraz +3 more
core +1 more source
Assessment of optic nerve and optic tract alterations in patients with orbital space-occupying lesions using probabilistic diffusion tractography [PDF]
AIM: To investigate the diffusion changes in both the optic nerve and optic tract in orbital space-occupying lesion patients with decreased visual acuity, and its clinical significance using probabilistic diffusion tractography (PDT).
Chun-Nan Wu +6 more
doaj +1 more source
Pathophysiologisch-serologische, bildgebende und klinische Charakteristika der Neuromyelitis Optica [PDF]
Hintergrund: Neuromyelitis optica-Spektrum-Erkrankungen (NMOSD) stellen eine Gruppe neuroinflammatorischer Erkrankungen dar, die mit dem klinischen Auftreten von Myelitiden und/oder Optikusneuritiden (ON) einhergeht.
Schumacher, Sophie
core +1 more source
Glaucoma is a leading cause of irreversible blindness, normally associated with dysfunction and degeneration of the trabecular meshwork (TM) as the primary cause.
Rong Du +5 more
doaj +1 more source

