Results 151 to 160 of about 1,830,086 (308)

Optic Nerve Head Morphology in Superior Segmental Optic Nerve Hypoplasia(SSOH), Primary Open-Angle-Glaucoma(POAG), and Healthy Patients

, 2017
To compare the optic nerve head structures and blood vessel angles among SSOH, POAG, and healthy ...
Lynn Shi; Jeffrey Odel; Ravivarn Jarukasetphon; Robert Ritch; Donald Hood
core  

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

Smarcc1 drives optic stalk patterning and optic nerve head astrocyte differentiation. [PDF]

Development
Zuk-Bar N, Ovadia S, Cui G, Obolensky A, Banin E, Ofri R, Jing N, Ashery-Padan R.   +7 more
europepmc   +1 more source

Optic nerve head topography and retinal structural changes in eyes with macrodisks: a comparative study with spectral domain optical coherence tomography

, 2016
Zeynep Kayaarasi Öztürker, Kadir Eltutar, Belma Karini, Sezin Özdogan Erkul, Özen Ayrancı Osmanbaşoğlu, Pınar Sultan Ophthalmology Department, Istanbul Research and Training Hospital, Istanbul, Turkey Purpose: To compare optic nerve
Ozturker ZK, Sultan P, Karini B, Eltutar K, Osmanbasoglu OA, Erkul SO   +5 more
core  

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

Advanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu, Jingfan Wang, Pengfei Ge, Qinyuan Gu, Hongying Li, Yuanyuan Fan, Haiyue Xie, Yangyang Lu, Yifan Lin, Xinjing Wu, Chengkun Wang, Ping Xie, Zizhong Hu   +12 more
wiley   +1 more source

OCT Assessment of Deep Optic Nerve Head, Subfoveal Choroidal Thickness, and Retinal Layers in Unilateral Anisometropic Amblyopia. [PDF]

Beyoglu Eye J
Çelenk EH, Turkcuoglu P.
europepmc   +1 more source

Correlation between optic nerve head structural parameters and glaucomatous visual field indices

, 2014
Kyoichi Mizumoto,1 Masahiko Gosho,2 Masahiro Zako1 1Department of Ophthalmology, Aichi Medical University, Nagakute, Aichi, Japan; 2Advanced Medical Research Center, Aichi Medical University, Nagakute, Aichi, Japan Abstract: We examined associations ...
Zako M, Gosho M, Mizumoto K
core  

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Optic Nerve Head Parameters and Their Associations With Axial Length and Refractive Status in Cynomolgus Macaques. [PDF]

Invest Ophthalmol Vis Sci
Luo R, Li Y, Xie R, Wang Z, Zhang Y, Zhan J, Chen K, Ye G, Yu J, Leng Y, Zhu Y, Zhuo Y.   +11 more
europepmc   +1 more source

Decoding the Neural Circuit Underlying Context‐Cue Association in Retrieval of Morphine Reward Memory

Advanced Science, EarlyView.
Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi, Guangying Li, Qian Yang, Rusun Liu, Linghan Gu, Mingmei Wang, John L. Waddington, Fuhai Ji, Xuechu Zhen   +8 more
wiley   +1 more source