Results 171 to 180 of about 1,830,086 (308)

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source

Hopx(+) optic nerve head-astrocytes counter neuronal stress and glaucoma damage. [PDF]

Proc Natl Acad Sci U S A
Bernstein SL, Mehrabian Z, Guo Y, Jouffroy J, Mead B, Tomarev S, Durmaz E, Epstein JA, Kronk A, Blackshaw S, Hoang T.   +10 more
europepmc   +1 more source

Strengthening Constitutive Motifs in Isotropic Fibrous Hydrogel for Exceptional Damage Resistance

Advanced Science, EarlyView.
An orientation‐free strategy is reported for fabricating damage‐resistant hydrogels by strengthening constitutive motifs in isotropic fibrous (IF) networks. Through nonsolvent quenching followed by salting‐out, IF networks are generated and their multiscale constituents are subsequently reinforced, yielding dense and crystalline isotropic nanofiber ...
Bolin Wan, Xule Yang, Liju Xu, Dong Qiu
wiley   +1 more source

Associations of Optic Nerve Head and Parapapillary Atrophy Changes With Retinal Nerve Fiber Layer and Ganglion Cell Complex Thinning in Healthy Eyes. [PDF]

Transl Vis Sci Technol
Li C, Cheng Y, Song L, Li M, Pan X, Xiang F, Wang Y, Ren J, Wang Z, Li Y, Guo L, Wei H, Shao X, Li S.   +13 more
europepmc   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

Optic nerve head drusen

Journal of Clinical Ophthalmology and Research
Srushti Rajendra Phirke, Sudhir Baburdikar   +1 more
doaj   +1 more source

Optic nerve head abnormalities in primary open-angle glaucoma and their associations with axial length. [PDF]

Jpn J Ophthalmol
Saito H, Wang W, Akiyama K, Aoki S, Shirato S, Sakata R, Aihara M, Honjo M.   +7 more
europepmc   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

Advanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu, Xin Yuan, Zilong He, Hong Jin, Jiayi Tian, Cong Chen, Yuanjing Liu, Xiang Zhang, Shidan Wen, Emilio Kropff, Chenglin Miao   +10 more
wiley   +1 more source

THE YIELDING OF THE OPTIC NERVE-HEAD IN GLAUCOMA [PDF]

British Journal of Ophthalmology, 1921
openaire   +2 more sources

Optic Nerve Head Granuloma from Sarcoidosis

We present a case of optic neuropathy with optic nerve head granuloma as the presenting sign of neurosarcoidosis. Initial patient presentation was notable for a chronic cough and worsening of vision in the left eye.
Nithya Shanmugam; Valerie Biousse
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