Results 111 to 120 of about 183,318 (235)

U-Net with spatial pyramid pooling for drusen segmentation in optical coherence tomography [PDF]

arXiv, 2019
The presence of drusen is the main hallmark of early/intermediate age-related macular degeneration (AMD). Therefore, automated drusen segmentation is an important step in image-guided management of AMD. There are two common approaches to drusen segmentation. In the first, the drusen are segmented directly as a binary classification task.
arxiv  

Extracting full information from OCT scans—signs of early age‐related macular degeneration within inner retinal layers by local neighbourhood statistics. Part I: Methodology

Ophthalmic and Physiological Optics, Volume 45, Issue 1, Page 231-246, January 2025.
Abstract Background and Objectives Associations between the occurrence of early age‐related macular degeneration (AMD) and alterations in retinal layer thicknesses have been reported based on classical processing of optical coherence tomography (OCT) data by noise removal and subsequent image segmentation.
Marcus Wagner, Julia Sommerer, Franziska G. Rauscher   +2 more
wiley   +1 more source

Young Adults With Anterior Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen Study. [PDF]

, 2020
PURPOSE: Optic disc drusen (ODD), present in 2% of the general population, have occasionally been reported in patients with nonarteritic anterior ischemic optic neuropathy (NA-AION). The purpose of this study was to examine the prevalence of ODD in young
Biousse, V, Bursztyn, L, Citirak, G, Costello, F, Crum, AV, Digre, K, Fard, MA, Fraser, CL, Fraser, JA, Hamann, S, Huna-Baron, R, Katz, B, Lawlor, M, Malmqvist, L, Newman, NJ, Optic Disc Drusen Studies Consortium, Peragallo, JH, Petzold, A, Sibony, PA, Subramanian, PS, Warner, JEA, Wegener, M, Wong, SH   +22 more
core  

The Ocular Manifestations of Individuals With Down Syndrome: A Systematic Review and Meta‐Analysis

Journal of Ophthalmology, Volume 2025, Issue 1, 2025.
Background: Down syndrome (DS) is the most common genetic cause of intellectual disability. Ocular manifestations occur frequently in people with DS (pwDS) but to date, there is no systematic review or meta‐analysis of these conditions across the lifespan.
Jessica A. Beresford-Webb, Emily Charlesworth, Shahina Pardhan, Valerie Wang, Megan Vaughan, Mary Igbineweka, Shahid H. Zaman, Shengjie Li   +7 more
wiley   +1 more source

Microvascular Changes Associated with Optic Disc Drusen: Case Report

Türk Oftalmoloji Dergisi, 2019
Optic disc drusen (ODD) is an important clinical entity that is sometimes misdiagnosed as papilledema because of elevated and blurred disc margins. A 17-year-old male who presented with headaches underwent detailed ophthalmological examination as well as
Özlem Biçer, Huban Atilla
doaj   +1 more source

Multiclass segmentation as multitask learning for drusen segmentation in retinal optical coherence tomography [PDF]

arXiv, 2019
Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom anatomical interfaces that define drusen, the outer boundary of the retinal pigment epithelium (OBRPE) and the Bruch's ...
arxiv  

Large-scale machine learning-based phenotyping significantly improves genomic discovery for optic nerve head morphology [PDF]

arXiv, 2020
Genome-wide association studies (GWAS) require accurate cohort phenotyping, but expert labeling can be costly, time-intensive, and variable. Here we develop a machine learning (ML) model to predict glaucomatous optic nerve head features from color fundus photographs. We used the model to predict vertical cup-to-disc ratio (VCDR), a diagnostic parameter
arxiv  

A feature agnostic approach for glaucoma detection in OCT volumes [PDF]

, 2018
Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of glaucoma. Previously, machine learning techniques have utilized segmentation-based imaging features such as the ...
arxiv   +1 more source

Múltiplos defeitos localizados da camada de fibras nervosas em um paciente com glioma de nervo óptico no olho contralateral: relato de caso [PDF]

, 2009
This case report describes a young non-glaucomatous patient with neurofibromatosis and previous history of optic nerve glioma, which developed multiple wedge-shaped retinal nerve fiber layer defects close to a chorioretinal scar in the fellow eye.
Lima, Verônica Castro, Magalhães, Fernanda Pedreira, Manso, Paulo Góis, Prata, Tiago dos Santos, Teixeira, Luiz Fernando   +4 more
core   +3 more sources

Mimickers of hydroxychloroquine retinal toxicity

Clinical &Experimental Ophthalmology, Volume 52, Issue 9, Page 1003-1015, December 2024.
Abstract Hydroxychloroquine (HCQ) retinal toxicity is an important entity that can be challenging to differentiate from its mimickers. Bull's eye maculopathy is the classical presentation of HCQ retinopathy; however, its differential includes several drug‐related retinal toxicities, inherited retinal disorders, and systemic conditions with associated ...
Peter Jones, Gagan Kalra, Mayss Al‐Sheikh, Jay Chhablani   +3 more
wiley   +1 more source