Results 41 to 50 of about 3,087 (193)

Optical coherence tomography demonstrating macular retinal nerve fiber thinning in advanced optic disc drusen

open access: yesOman Journal of Ophthalmology, 2014
Optic disc drusen (ODD) are extracellular proteinaceous excrescences in the optic nerve head. They enlarge over time and can cause damage to nerve fibers with resulting loss of visual field.
Ali Hassan, Pieter Gouws
doaj   +1 more source

The Angioarchitecture of the Optic Nerve Head in Patients with Optic Disc Drusen [PDF]

open access: yesNeuro-Ophthalmology, 2019
The aim was to analyse the optic disc angioarchitecture in optic disc drusen (ODD) patients using computer-based fundus analysis in a case-control study. Compared with controls the ODD group had a significantly more centralised central retinal artery (CRA) emergence (p < 0.001) and primary CRA branching (p = 0.008), a higher number of CRA bifurcations (
Vahlgren, Julie   +5 more
openaire   +3 more sources

Foundation Models in Diagnosis of Ophthalmic Diseases: Construction and Application

open access: yesEye &ENT Research, Volume 3, Issue 2, Page 45-58, June 2026.
ABSTRACT Artificial intelligence holds promise for addressing the uneven distribution of medical resources across different regions. Compared with convolutional neural network models, foundation models offer significant advantages: on one hand, their pre‐training does not rely on massive labeled data; on the other hand, they possess the capability to ...
Xiaolu Huang   +7 more
wiley   +1 more source

Advances in origin, evolution, and pathogenesis of optic disc drusen: A narrative review

open access: yesIndian Journal of Ophthalmology
Optic disc drusen (ODD) is acellular calcified deposits found mainly in front of the lamina cribrosa within the optic nerve. It can cause chronic or acute vision loss.
Xiyuan Liu, Yan Yan
doaj   +1 more source

Evaluation of retinal nerve fiber layer thickness in a patient with bilateral optic disc drusen

open access: yesRevista Brasileira de Oftalmologia, 2015
Optic disc drusen (ODD) is the accumulations of calcified hyaline-like material within the substance of the optic nerve head. Optic disc drusen, especially if it is bilateral, may mimic the clinical presentation of papilledema.
Alime Gunes   +3 more
doaj   +1 more source

Volumetric Measurement of Peripapillary Hyperreflective Ovoid Masslike Structures in Patients with Optic Disc Drusen

open access: yesOphthalmology Science, 2022
Purpose: To develop a method to determine the volume of peripapillary hyperreflective ovoid masslike structures (PHOMS) and to examine the correlation between PHOMS and anatomic optic nerve head characteristics in a large cohort of patients with optic ...
Morten Jørgensen, MD   +4 more
doaj   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page e277-e291, May 2026.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger   +8 more
wiley   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

open access: yesClinical &Experimental Ophthalmology, Volume 54, Issue 3, Page 382-397, April 2026.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia   +3 more
wiley   +1 more source

Optic nerve head drusen: same presentation, different workup [PDF]

open access: yes, 2014
Objective/Purpose: To report two young patients with optic nerve head drusen in wich one was interpreted initially as pappiledema. Discuss the OCT and the autofluorescence retinography optic nerve head drusen characteristics. Materials/Patients: Patient
Ramalho, M   +4 more
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