Results 41 to 50 of about 2,990 (157)

Volumetric Measurement of Peripapillary Hyperreflective Ovoid Masslike Structures in Patients with Optic Disc Drusen

Ophthalmology Science, 2022
Purpose: To develop a method to determine the volume of peripapillary hyperreflective ovoid masslike structures (PHOMS) and to examine the correlation between PHOMS and anatomic optic nerve head characteristics in a large cohort of patients with optic ...
Morten Jørgensen, MD, Lasse Malmqvist, MD, PhD, Alexander E. Hansen, BSc, J. Alexander Fraser, MD, Steffen Hamann, MD, PhD   +4 more
doaj   +1 more source

Incidentally discovered optic nerve head drusen

Journal of the Belgian Society of Radiology, 2014
A 34-year-old white woman presented for holocephalic headaches following a blow to the head. She did not mention any vision disturbance. Computed tomography was performed and displayed bilateral calcific deposits in the disk optic areas consistent with optic nerve head drusen.
Gérard, L, Gudelj, M, Houbart, MA, Tshibanda, L   +3 more
openaire   +5 more sources

HSPE1 deficiency underlies the crosstalk between metabolic dysfunction‐associated steatotic liver disease and age‐related macular degeneration

VIEW, EarlyView.
Rare‐earth ions act as multifunctional modifiers in perovskite solar cells by improving charge transport, suppressing oxygen vacancies, passivating defects, promoting grain growth, and enabling redox‐mediated stabilization. In addition, RE‐doped layers can expand spectral utilization through upconversion and downconversion, thereby enhancing light ...
Jiaqi Meng, Alimire Maihemuti, Yuan Yuan, Chao Chen, Mengchao Zhu, Hao Wang, Furong Zhu, Zhaodi Che, Jia Xiao, Xiangjia Zhu   +9 more
wiley   +1 more source

Ischaemic Optic Neuropathy After Cardiac Surgery: A Systematic Review and Meta‐Analysis of Incidence and Risk Factors

ANZ Journal of Surgery, EarlyView.
Across 11 observational studies comprising 6 471 577 patients, the pooled incidence of ischaemic optic neuropathy after cardiac surgery was approximately 1.5 cases per 10 000 procedures. Coronary artery disease, peripheral vascular disease and anaemia were associated with increased odds of ION, although these findings should be interpreted in the ...
Daud Mutahar, Ammar Zaka, Amitouj S. Sidhu, Shahi Goswami, Aditi Singh, Jordan Ng, Brandon Stretton, Joshua G. Kovoor, Aashray K. Gupta, Stephen Bacchi, Weng Onn Chan, Celia Chen   +11 more
wiley   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin, Karolina Kaminska, Marco Cattaneo, Enrico Ambrosini, Carmen Ayuso, Almudena Ávila‐Fernández, Béatrice Bocquet, Luisa Coutinho‐Santos, Benedetto Falsini, Lidia Fernandez‐Caballero Palomeque, Bohdan Kousal, Petra Liskova, Inmaculada Martín‐Mérida, María Juliana Ballesta‐Martínez, Daan Panneman, Susanne Roosing, Isabelle Meunier, José M. Millán, Monika Pankievič, Irene Perea‐Romero, Virginie Peter, Giorgio Placidi, Cristina Santos, Francesca Simonelli, Ana Berta Sousa, Francesco Testa, Marie Vajter, Marianna Weener, Mathieu Quinodoz, Carlo Rivolta, Giacomo Calzetti   +30 more
wiley   +1 more source

Misdiagnosis of missed diagnosis

TNOA Journal of Ophthalmic Science and Research, 2018
Papilledema is swelling of the optic nerve head, a sign of increased intracranial pressure. It can have underlying life-threatening etiologies such as intracranial space-occupying lesions or meningitis.
Sadiqha S Banu, Malarchelvi Palani, Pratheeba Devi Nivean, M Nivean   +3 more
doaj   +1 more source

From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics

Advanced Therapeutics, Volume 9, Issue 10, October 2026.
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker, Ka‐Ying Wong, Liping Zhou, Man‐Sau Wong, Juewen Liu   +4 more
wiley   +1 more source

Bilateral Non Arteritic Anterior Ischemic Optic Neuropathy Associated With Optic Nerve Head Drusen And Vascular Risk Factors

Delhi Journal of Ophthalmology, 2021
We report case history of 52 year old male who presented with sudden painless diminution of vision in right eye and with similar complaint of diminution of vision in left eye six months back.
Eathi Tuli, Aakanksha Sharma, Gaurav Sharma, Shalu Gupta   +3 more
doaj   +1 more source

Imaging of Optic Nerve Head Drusen [PDF]

Journal of Glaucoma, 2009
To demonstrate a new algorithm that can determine the shape, location, and volume of optic nerve head drusen (ONHD), which were imaged with spectral domain optical coherence tomography (SDOCT).One exenteration patient and 4 glaucoma patients with bilateral ONHD were recruited from the Massachusetts Eye and Ear Infirmary and from a private practice ...
Yi, K., Mujat, M., Sun, Wei, Burnes, D. L., Latina, M. A., Lin, D. T., Deschler, D. G., Rubin, P. A. D., Park, B. H., de Boer, J.F., Chen, T.   +10 more
openaire   +3 more sources

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source