Results 61 to 70 of about 2,990 (157)

Trends and Clinical Characteristics of Pediatric Patients Presenting to an Ophthalmology Emergency Department with an Initial Diagnosis of Optic Nerve Head Elevation

Clinical Ophthalmology, 2022
Kara M Cavuoto, Zahra Markatia, Annika Patel, Carla J Osigian Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USACorrespondence: Kara M Cavuoto, Department of Ophthalmology, Bascom ...
Cavuoto KM, Markatia Z, Patel A, Osigian CJ   +3 more
doaj  

In-vivo high resolution imaging of optic nerve head drusen using spectral-domain Optical Coherence Tomography

BMC Medical Imaging, 2010
Background Optic nerve head drusen (ONHD) are white calcareous deposits, seen either superficially on the optic nerve head or buried within it. Diagnosis of ONHD is made by one or more ways: clinical exam, autofluorescence, ultrasound of the optic nerve,
Brar Vikram S, Grover Sandeep, Storm Laura, Murthy Ravi K, Chalam Kakarla V   +4 more
doaj   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

Acta Ophthalmologica, Volume 104, Issue 3, Page e277-e291, May 2026.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger, Safa Mohanna, Sohrab Ferdowsi, Sonja Simon‐Zoula, Oliver Pfäffli, Christoph Amstutz, Lucas M. Bachmann, Michael A. Thiel, Martin K. Schmid   +8 more
wiley   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

Clinical &Experimental Ophthalmology, Volume 54, Issue 3, Page 382-397, April 2026.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia, Dimitrios Kazantzis, Guy S. Negretti, Mandeep S. Sagoo   +3 more
wiley   +1 more source

Case series: The value of fundus autofluorescence in inherited macular disease

Optometry and Vision Science, Volume 103, Issue 3, March 2026.
ABSTRACT Purpose To evaluate the diagnostic utility of fundus autofluorescence (FAF) imaging in identifying and characterizing phenotypically classified inherited macular dystrophies. In this way, we aim to provide methods by which eye care practitioners can link FAF imaging and other clinical results or imaging modalities to aid their clinical ...
Marina Guro, Henrietta Wang, Jack Phu, Nimesh B. Patel, Kaitlyn A. Sapoznik, Hamza Shah, Michael Kalloniatis   +6 more
wiley   +1 more source

Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review

BioFactors, Volume 52, Issue 1, January/February 2026.
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra, Chia‐Che Ku, Ying‐Chu Lin, Yi‐Chun Tsai, Deng‐Chyang Wu, Yukio Mitsui, Maki Satou, Yuuki Tanaka, Shigeo Saito, Kazunari K. Yokoyama   +9 more
wiley   +1 more source

Multicolor imaging in optic disc swelling

Indian Journal of Ophthalmology, 2017
Differentiating optic disc edema (ODE) from pseudo optic disc edema (PODE) continues to pose a diagnostic dilemma. Current report highlights the role of multicolor imaging (MC) in differentiating ODE from PODE.
Nicey Roy Thomas, Prachi Subhedar Ghosh, Maitreyi Chowdhury, Kumar Saurabh, Rupak Roy   +4 more
doaj   +1 more source

A Bayesian‐Optimized Ensemble Deep Learning Framework for Automated Detection and Classification of Retinal Diseases in Ghana Using OCT Images

Applied Computational Intelligence and Soft Computing, Volume 2026, Issue 1, 2026.
Retinal diseases pose a significant global health challenge due to their potential to cause severe visual impairment and blindness. This study aimed to develop a robust deep learning ensemble framework for the automated detection and classification of retinal diseases from optical coherence tomography (OCT) images.
Gifty Duah, Eric Nyarko, Gideon Nana Amo, Theophilus Dwamena Frimpong, Anani Lotsi, Pramita Mishra   +5 more
wiley   +1 more source

Comparative study of optic nerve head optical coherence tomography in papilledema versus drusen

Journal of the Egyptian Ophthalmological Society
Background Papilledema can cause permanent visual impairment, while optic nerve head drusen (ONHD) is typically benign. Spectral domain optic coherence tomography (SD-OCT) is essential for differentiating these conditions, providing high-resolution ...
Abla M.A.M. Yamani, Adel G.Z. Galal, Gerges F.Y. Ishak   +2 more
doaj   +1 more source