Results 71 to 80 of about 3,087 (193)
Ocular changes as potential biomarkers for early diagnosis of Alzheimer's disease
Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. AD diagnosis often involves a thorough assessment, including clinical evaluation, cognitive testing, medical history examination, genetic testing, and biomarker analysis. Currently, the invasive nature and high costs of biomarker testing,
Purna Chandra Poudel +6 more
wiley +1 more source
Long term follow-up of retinal nerve fiber layer thickness in eyes with optic nerve head drusen
, 2003 Purpose. To investigate the effect of optic nerve head drusen (ONHD) on the retinal nerve fiber layer (RNFL) thickness during follow-up ...
Ustundag, C +5 more
core +1 more source
Clinical &Experimental Ophthalmology, Volume 53, Issue 6, Page 682-697, August 2025.ABSTRACT Optical coherence tomography angiography is a burgeoning imaging modality in Ophthalmology. In this review, we outline the breadth of potential utility for optical coherence tomography angiography for diagnosis and prognostication in neuro‐ophthalmology.
Marzieh Tahmasebi Sarvestani +2 more
wiley +1 more source
Aging Cell, Volume 24, Issue 7, July 2025.Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox +13 more
wiley +1 more source
European Journal of Neurology, Volume 32, Issue 7, July 2025.This prospective cross‐sectional study screened 27 patients with inflammatory polyradiculoneuropathy (IPN) for signs of intracranial hypertension (IH) using multimodal ophthalmological assessments (fundoscopy, perimetry, OCT, ultrasonography). Signs of IH were identified in 37% of patients.
Stefan Macher +13 more
wiley +1 more source
Optic Nerve Head Drusen and Ischemic Optic Neuropathy
, 2002 Ischemic optic neuropathy is a well recognized but rare association with optic nerve head ...
Andrew G. Lee; Cari Lyle; Rosa Tang; Jade Schiffmann; Randy Kardon; Michael Wall; Michael Mabert
core
Assessment of Optic Nerve Head Drusen Using Enhanced Depth Imaging and Swept Source Optical Coherence Tomography [PDF]
, 2014 BACKGROUND: Optic nerve head drusen (ONHD) are calcific deposits buried or at the surface of the optic disc. Although ONHD may be associated with progressive visual field defects, the mechanism of drusen-related field loss is poorly understood.
Tatham, Andrew J +3 more
core +1 more source
Optical coherence tomography angiography in nonarteritic anterior ischemic optic neuropathy due to optic nerve head drusen [PDF]
, 2020 Optic nerve head drusen (ONHD) are typically benign hyaline and calcified concretions located within the optic nerve. Initially asymptomatic, they can increase slowly in size and number over time, and they can cause mechanical stress at the axons of the ...
Montorio D. +3 more
core +1 more source
Multicolor imaging in optic disc swelling
Indian Journal of Ophthalmology, 2017 Differentiating optic disc edema (ODE) from pseudo optic disc edema (PODE) continues to pose a diagnostic dilemma. Current report highlights the role of multicolor imaging (MC) in differentiating ODE from PODE.
Nicey Roy Thomas +4 more
doaj +1 more source
Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study
Movement Disorders, Volume 40, Issue 6, Page 1123-1133, June 2025.Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon +3 more
wiley +1 more source