Results 51 to 60 of about 2,990 (157)

Clinical and morpho-functional results of a second examination of a patient with optic nerve head drusen taken after a long-time interval (27 years)

Российский офтальмологический журнал
Optic disc drusen (ODD) is a bilateral anomaly of the optic nerve, in which hyaline calcified intercellular inclusions appear in the optic disc head area in front of the cribriform plate.
E. E. Ioyleva, E. A. Kabanova, S. I. Belyanina   +2 more
doaj   +1 more source

Optical coherence tomography in the evaluation of disc edema

Kerala Journal of Ophthalmology, 2019
Optic disc oedema is a common clinical problem where the ophthalmologist plays an important role in the diagnosis, management. Many optic nerve diseases can cause disc oedema like papilloedema, papillitis, anterior ischaemic optic neuropathy, central ...
Deepa Gaur, H Vijaya Pai
doaj   +1 more source

The Role of Optical Coherence Tomography Angiography in Optic Nerve Head Edema: A Narrative Review

Journal of Ophthalmology, 2022
Optic nerve head (ONH) edema is a clinical manifestation of many ocular and systemic disorders. Ocular and central nervous system imaging has been used to differentiate the underlying cause of ONH edema and monitor the disease course.
Narges Karrabi, Sadid Hooshmandi, Alireza Amirabadi, Danial Roshandel, Kiana Hassanpour, Mohammad Pakravan   +5 more
doaj   +1 more source

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

A Review of Artificial Intelligence in Ophthalmology: Key Aspects, Challenges, and Future Directions

Eye &ENT Research, Volume 3, Issue 3, Page 125-154, September 2026.
ABSTRACT Artificial intelligence (AI) is increasingly reshaping ophthalmology because the specialty depends heavily on structured imaging, quantitative measurements, and repeatable diagnostic workflows. This review provides a clinically grounded and translationally oriented synthesis of AI in ophthalmology, covering methodological foundations ...
Partha Pratim Ray
wiley   +1 more source

Revised Swedish visual field standards for a driver's licence: Threshold perimetry as a predictor of eligibility according to the current Swedish and current Norwegian suprathreshold standards

Acta Ophthalmologica, Volume 104, Issue 6, Page e709-e717, September 2026.
Abstract Purpose To explore whether threshold perimetry can predict fulfilment of the current Swedish and current Norwegian Esterman perimetry standards for Group 1 driver's licence, and differences in compliance between the former and current Swedish visual field standards.
Wid Saadi, Tomas Bro, Susanna Sagerfors
wiley   +1 more source

Coexistence of Optic Nerve Head Drusen and Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Taiwanese Male

Kaohsiung Journal of Medical Sciences, 2009
We report the case of a 38-year-old male patient with a 1-year history of progressively blurred vision in his left eye. He visited our clinic and underwent a series of ophthalmologic examinations including computed tomography, fluorescein angiography and
Yo-Chen Chang, Rong-Kung Tsai
doaj   +1 more source

CRB1 ‐Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow‐Up

Clinical &Experimental Ophthalmology, Volume 54, Issue 7, Page 917-931, September/October 2026.
ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu, Xuan‐Thanh‐An Nguyen, Mays Talib, Mary J. van Schooneveld, Jan Wijnholds, Maria M. van Genderen, Jos Twisk, Nicoline E. Schalij‐Delfos, Caroline C. W. Klaver, Ralph J. Florijn, Jacoline B. ten Brink, Magda A. Smoor, L. Ingeborgh van den Born, Carel B. Hoyng, Alberta A. H. J. Thiadens, Camiel J. F. Boon   +15 more
wiley   +1 more source

ApoE‐ and Cfh‐deficient mice exhibit structural and molecular features of human early–intermediate retinal degeneration

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1420-1435, July 2026.
Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde, Maite Moreno Orduña, Jaione Bezunartea, Idoia Belza, Ainara Chas, Laura Fernández‐Sánchez, Nicolás Cuenca Navarro, Alfredo García‐Layana, Patricia Fernández‐Robredo, María Hernández   +9 more
wiley   +1 more source

Foundation Models in Diagnosis of Ophthalmic Diseases: Construction and Application

Eye &ENT Research, Volume 3, Issue 2, Page 45-58, June 2026.
ABSTRACT Artificial intelligence holds promise for addressing the uneven distribution of medical resources across different regions. Compared with convolutional neural network models, foundation models offer significant advantages: on one hand, their pre‐training does not rely on massive labeled data; on the other hand, they possess the capability to ...
Xiaolu Huang, Guanran Zhang, Jiayu Xu, Shuyang Chen, Yanrong Li, Xiaodong Sun, Yanlin Qu, Huixun Jia   +7 more
wiley   +1 more source