Results 11 to 20 of about 1,469,459 (252)

Cell proliferation and apoptosis in optic nerve and brain integration centers of adult trout Oncorhynchus mykiss after optic nerve injury

Neural Regeneration Research, 2016
Fishes have remarkable ability to effectively rebuild the structure of nerve cells and nerve fibers after central nervous system injury. However, the underlying mechanism is poorly understood.
Evgeniya V Pushchina, Sachin Shukla, Anatoly A Varaksin, Dmitry K Obukhov   +3 more
doaj   +2 more sources

Differences in optic nerve structure between individuals of predominantly African and European ancestry: Implications for disease detection and pathogenesis

Clinical Ophthalmology, 2008
Christopher A GirkinUniversity of Alabama at Birmingham School of Medicine, Birmingham, AL, USAAbstract: Glaucoma disproportionately affects individual of African ancestry. Additionally, racial differences in the optic nerve head have been well described
Christopher A Girkin
doaj   +1 more source

The role of monocytes in optic nerve injury. [PDF]

Neural Regen Res, 2023
Monocytes, including monocyte-derived macrophages and resident microglia, mediate many phases of optic nerve injury pathogenesis. Resident microglia respond first, followed by infiltrating macrophages which regulate neuronal inflammation, cell ...
Liu X, Liu Y, Khodeiry MM, Lee RK.
europepmc   +2 more sources

Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]

, 2009
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S., Hamilton, Nicola; id_orcid, Hamilton, N., Butt, Arthur, Hubbard, Paul, Butt, Arthur M., Hamilton, N, Hubbard, P., Butt, AM   +8 more
core   +1 more source

Optic nerve as a source of activated retinal microglia post-injury

Acta Neuropathologica Communications, 2018
Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons.
Neal D. Heuss, Mark J. Pierson, Heidi Roehrich, Scott W. McPherson, Andrea L. Gram, Ling Li, Dale S. Gregerson   +6 more
doaj   +1 more source

ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]

, 2004
Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Coffin, RS, Hossain-Ibrahim Kismet, Mason, MRJ, Lieberman AR, Lieberman, AR, Mason Matthew RJ, Hossain-Ibrahim, K, David Hunt, Winterbottom, J, Anderson, PN, Hunt David, AR Lieberman, Kismet Hossain-Ibrahim, Anderson PN, Coffin Robert S, Hunt, D, PN Anderson, Matthew RJ Mason, Robert S Coffin, Winterbottom Julia, Julia Winterbottom   +20 more
core   +1 more source

Neurolin expression in the optic nerve and immunoreactivity of Pax6-positive niches in the brain of rainbow trout (Oncorhynchus mykiss) after unilateral eye injury

Neural Regeneration Research, 2019
In contrast to astrocytes in mammals, fish astrocytes promote axon regeneration after brain injury and actively participate in the regeneration process. Neurolin, a regeneration-associated, Zn8-labeled protein, is involved in the repair of damaged optic ...
Evgeniya V Pushchina, Anatoly A Varaksin
doaj   +1 more source

Human umbilical cord blood-derived stem cells and brain-derived neurotrophic factor protect injured optic nerve: viscoelasticity characterization

Neural Regeneration Research, 2016
The optic nerve is a viscoelastic solid-like biomaterial. Its normal stress relaxation and creep properties enable the nerve to resist constant strain and protect it from injury.
Xue-man Lv, Yan Liu, Fei Wu, Yi Yuan, Min Luo   +4 more
doaj   +1 more source

Serotonin transporter-mediated molecular axis regulates regional retinal ganglion cell vulnerability and axon regeneration after nerve injury

PLoS Genetics, 2021
Molecular insights into the selective vulnerability of retinal ganglion cells (RGCs) in optic neuropathies and after ocular trauma can lead to the development of novel therapeutic strategies aimed at preserving RGCs.
Rody Kingston, Dwarkesh Amin, Sneha Misra, Jeffrey M. Gross, Takaaki Kuwajima   +4 more
doaj   +2 more sources

Melanopsin ganglion cells are the most resistant retinal ganglion cell type to axonal injury in the rat retina.

PLoS ONE, 2014
We report that the most common retinal ganglion cell type that remains after optic nerve transection is the M1 melanopsin ganglion cell. M1 ganglion cells are members of the intrinsically photosensitive retinal ganglion cell population that mediates non ...
Luis Pérez de Sevilla Müller, Allison Sargoy, Allen R Rodriguez, Nicholas C Brecha   +3 more
doaj   +1 more source