Results 11 to 20 of about 10,950 (228)
Frontiers in Neuroscience, 2021 Optic neuritis is a frequent first symptom of multiple sclerosis (MS) for which corticosteroids are a widely employed treatment option. The Optic Neuritis Treatment Trial (ONTT) reported that corticosteroid treatment does not improve long-term visual ...
Tsen-Hsuan Lin +13 more
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Treatment of Acute Optic Neuritis [PDF]
Archives of Ophthalmology, 2008 inconclusive because of small sample size. In the 1980s, the Optic Neuritis Treatment Trial was developed to evaluate corticosteroid treatment for optic neuritis. This multicenter randomized clinical trial, supported by the National Eye Institute, was designed to answer the following questions: (1) Does treatment with either oral prednisone or ...
Roy W, Beck, Robin L, Gal
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The Optic Neuritis Treatment Trial
Journal of Neuro-Ophthalmology, 1995 The publications of the Optic Neuritis Treatment Trial (1-3) have generated some misconceptions about the study design and the results. In this article, we offer a digest of how the ONTT was conducted, what it showed, how its results may affect management of optic neuritis, and answers to some of the most frequently asked questions about the validity ...
Roy W. Beck, Jonathan D. Trobe
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Should Patients with Optic Neuritis Be Treated with Steroids? [PDF]
, 2015 Purpose of review: Optic neuritis is the most common cause of optic neuropathy in young adults. High-dose intravenous corticosteroids (IVCS) were established as the standard of treatment for acute optic neuritis via the Optic Neuritis Treatment Trial ...
Mackay, Devin D.
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Evidence in practice-number 8:What is the prognosis of optic neuritis? How often does it lead to multiple sclerosis? [PDF]
, 2005 Gearing components are an example for widely used machining parts in engines. Nowadays the development and optimization of materials and process chains are driven towards a concurrent improvement of final product properties and production efficiency ...
Sanders, Sharon +5 more
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Monitoring retinal changes with optical coherence tomography predicts neuronal loss in experimental autoimmune encephalomyelitis. [PDF]
, 2019 BACKGROUND:Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have reported RGC loss.
Aktas, Orhan +18 more
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A longitudinal study of abnormalities on MRI and disability from multiple sclerosis [PDF]
, 2002 Background: In patients with isolated syndromes that are clinically suggestive of multiple sclerosis, such as optic neuritis or brain-stem or spinal cord syndromes, the presence of lesions as determined by T2-weighted magnetic resonance imaging (MRI) of ...
Brex, P.A. +5 more
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A practical approach to the diagnosis and management of optic neuritis
Annals of Indian Academy of Neurology, 2022 Optic neuritis (ON), as an umbrella term, refers to a spectrum of inflammatory optic neuropathies arising from a myriad of potential causes. In its most common form, “typical” ON presents as a unilateral, painful subacute vision loss event in young ...
Etienne Benard-Seguin, Fiona Costello
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Arbeiten zur Optischen Kohärenztomographie, Magnetresonanzspektroskopie und Ultrahochfeld-Magnetresonanztomographie [PDF]
, 2019 Abstrakt (Deutsch) Hintergrund: Die Multiple Sklerose ist eine der häufigsten neurologischen Erkrankungen, die zu Behinderung bereits im jungen Erwachsenenalter führen kann.
Pfüller, Caspar Friedrich
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Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
, 2003 Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
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