Results 121 to 130 of about 49,888 (287)

Retinal and Choroidal Microvasculature in Nonarteritic Anterior Ischemic Optic Neuropathy: An Optical Coherence Tomography Angiography Study.

Investigative Ophthalmology and Visual Science, 2018
Purpose To analyze retinal and choroidal microvasculature in patients with nonarteritic anterior ischemic optic neuropathy (NAION) by using optical coherence tomography angiography (OCT-A). Methods In this case-control retrospective observational study,
Edouard Augstburger, P. Zéboulon, C. Keilani, C. Baudouin, A. Labbé   +4 more
semanticscholar   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Anterior ischemic optic neuropathy secondary to interferon alpha

Zdravniški Vestnik, 2005
Background: Anterior ischemic optic neuropathy rarely occurs with interferon alpha therapy. The mechanism by which interferon induces anterior ischemic optic neuropathy is unknown.Methods: A 62-year-old man presented with complaints of sudden severe loss
Stanka Godina-Kariž, Nives Avancini, Stojan Kariž   +2 more
doaj  

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter, Niedermeier, W., Schneider, Uwe   +2 more
core   +1 more source

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen, Lene Terslev, Uffe M. Døhn, Viktoria Fana, Jane M. Brittain, Anne K. Wiencke, Steffen Heegaard, Mads R. Jensen, Oliver N. Klefter, Yousif Subhi, Steffen Hamann   +10 more
wiley   +1 more source

Is There a Causal Link Between GLP‐1 Receptor Agonists and Non‐Arteritic Anterior Ischaemic Optic Neuropathy? A Critique of the Clinical Evidence

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are widely used for managing Type 2 diabetes and obesity, with well‐documented and significant cardiometabolic benefits. Recent observational reports and pharmacovigilance data have raised concerns about a possible association between GLP‐1RAs‐particularly semaglutide‐ and non‐arteritic ...
Helen V. Danesh‐Meyer, Joseph F. Rizzo III   +1 more
wiley   +1 more source

Macular ganglion cell complex measurement in bilateral retrobulbar optic neuropathy without a relative afferent pupillary defect

International Medical Case Reports Journal, 2018
Masatoshi Haruta, Hiroyuki Ohshima, Ryoji Yamakawa Department of Ophthalmology, Kurume University School of Medicine, Kurume, Japan Purpose: This study aimed to demonstrate the clinical usefulness of measuring the macular ganglion cell complex (GCC) for ...
Haruta M, Ohshima H, Yamakawa R
doaj  

Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension. [PDF]

, 2020
Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence-related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset ...
Jabari, Mary, Krawczyk, Michal, Nguyen Huu, Viet Anh, Palomino La Torre, Claudia, Rocha, Lorena Raquel, Skowronska-Krawczyk, Dorota, Weinreb, Robert N, Xu, Qianlan   +7 more
core  

New strategies for neuroprotection in glaucoma,a disease that affects the central nervous system [PDF]

, 2016
Glaucoma is a disease where retinal ganglion cells (RGC) are specifically affected though a number of evidences endorse the hypothesis that glaucoma is a neuro-degenerative disorder of the central nervous system and suggest a possible connection between ...
Bagetta, G, Floris, R, Garaci, F, Giannini, C, Martucci, A, Morrone, LA, Nucci, C, Russo, R   +7 more
core   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source