Results 151 to 160 of about 1,360,810 (251)
The sorting nexin Snx21 promotes flotillin‐mediated endocytosis
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs +9 more
wiley +1 more source
F2b09 Optic Disc Swelling from Malignant Optic Nerve Glioma
Malignant optic nerve glioma of adulthood with blindness and optic disc edema. Right image shows white material extruded from the swollen optic disc. This material is myelin being squeezed into the eye from the nerve infarction.
William F. Hoyt, MD
core
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad +6 more
wiley +1 more source
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley +1 more source
Visual outcomes and predictors in optic pathway glioma: a single centre study. [PDF]
Bowman R +12 more
europepmc +1 more source
Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega +10 more
wiley +1 more source
Bibliometric mapping of the 100 most-cited publications on optic nerve and optic pathway glioma: A cross-sectional bibliometric analysis. [PDF]
Shah MH +7 more
europepmc +1 more source
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source
Novel Germline ELP1 Splice-Acceptor Variant in NF1-Negative Optic Pathway Glioma: Expanding the Clinical Spectrum Associated With ELP1 Variation. [PDF]
Latifi A +3 more
europepmc +1 more source

