Results 41 to 50 of about 1,360,810 (251)
, 2017 Pediatric optic pathway gliomas share common clinicoradiographic characteristics and are typically World Health Organization grade I/II astrocytomas. Management of these tumors presents a therapeutic challenge based on host age as well as anatomic location.
Julie A. Bradley +2 more
+4 more sources
Overall Survival for the whole population with optic pathway glioma.
, 2015 Overall Survival for the whole population with optic pathway glioma.
Jacques Grill (87832) +8 more
core +1 more source
(Pro)renin receptor is crucial for glioma development via the Wnt/β-catenin signaling pathway [PDF]
, 2017 香川大学Kagawa University博士（医学）OBJECTIVE The (pro)renin receptor (PRR) plays an essential role in the early development of the central nervous system by activating the Wnt/β-catenin signaling pathway. The authors investigated the potential role of the PRR in
コウチ, マサアキ +2 more
core +1 more source
Acute post-partum vision loss due to pilocytic astrocytoma
American Journal of Ophthalmology Case Reports, 2020 Purpose: We report an unusual case of a thirty-three-year-old woman who presented with acute unilateral vision loss following pregnancy and was ultimately discovered to have a pilocytic astrocytoma of the optic nerve.
Natalie A. Homer +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Torkildsen shunt as an option for hydrocephalus associated with optic pathway glioma
Archives of Pediatric Neurosurgery, 2021 Hydrocephalus caused by optic pathway glioma (OPG) is most often treated with a ventriculoperitoneal shunt (VPS), but this treatment may present complications such as ascites. Hence, ventriculocisternal shunt is an option worth considering.
Aldo José F da Silva
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Novel treatments in optic pathway gliomas
Frontiers in Ophthalmology, 2022 Optic pathway gliomas (OPG) are primary tumors of the optic nerve, chiasm, and/or tract that can be associated with neurofibromatosis type 1 (NF1). OPG generally have a benign histopathology, but a variable clinical course. Observation is generally recommended at initial diagnosis if vision is stable or normal for age, however, treatment may include ...
Maheshwari, Akash +4 more
openaire +2 more sources
Visual Field Outcomes in Optic Pathway Glioma After Bevacizumab Therapy
, 2022 Systemic bevacizumab is a promising therapy for optic pathway glioma (OPG) radiographic tumor burden1, but little is known about its impact on visual function2,3.
Daniel Nelson; Benjamin Siegel; Tobey MacDonald; David Wolf; Jason Peragallo
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source