Results 131 to 140 of about 661,976 (251)

Segmental Atrophy - Hemianopic (Band) Atrophy from Eight Optic Tract Injury

Segmental Atrophy - Band atrophy from right optic tract injury. This eye has a nasal hemianopia. Its disc shows temporal pallor with an intact nasal nerve fiber layer. Pair with IIA2C_7b. Anatomy: Optic disc. Pathology: Right optic tract injury.
William F. Hoyt, MD
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Optic chiasm, optic tract and deep white demyelination: an unusual distribution of myelin oligodendrocyte glycoprotein-associated demyelination (MOGAD), case report and review of literature. [PDF]

BMJ Case Rep, 2022
Lasrado A, Chattannavar G, Sachdeva V, Kekunnaya R.   +3 more
europepmc   +1 more source

Test Your Knowledge: Optic Tract

The Test Your Knowledge series are multiple choice questions intended to complement NANOS Illustrated Curriculum for Neuro-Ophthalmology. The questions in this set cover the optic tract, the region of the visual pathway found posterior to optic chiasm ...
Ryung San Lee; Amanda Dean Henderson
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A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Segregation of functionally distinct axons in the monkey's optic tract.

, 1988
The classical neuro-ophthalmologic literature describes the organization of the primate's optic tract as containing a single topographic representation of the complete contralateral visual hemifield.
Reese, BE, Cowey, A, B. E. Reese, A. Cowey, Cowey, Alan   +4 more
core   +1 more source

Deep‐Learning‐Driven High‐Fidelity In Vivo Hyperspectral Fluorescence Imaging Under Extreme Photon‐Limited Conditions

Advanced Science, EarlyView.
Highly overlapping fluorescent signals become distinguishable in photon‐limited living organisms via advanced imaging with intelligent reconstruction. The resulting in vivo hyperspectral imaging capability reveals nanoplastic uptake and circulation in live zebrafish, providing a new approach for studying complex biological and environmental processes ...
Renjian Li, Shutao Wu, Kaixiang Li, Zhenyu An, Yuwen Ben, Guiye LI, Sunil Kumar, James Mcginty, Tawfique Hasan, Songnian Fu, Meng Zhang, LingLing Chen   +11 more
wiley   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

Advanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang, Zhijian Xu, Ye Tian, Yao Zhang, Zhe Cheng, Yanhai Wang   +5 more
wiley   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

An Acute Presentation of a Cavernous Hemangioma of the Optic Nerve, Optic Chiasm and Optic Tract

, 2013
Central nervous system cavernous malformations affect roughly 0.5% of the population and can occur anywhere in the brain and spinal cord. Cavernous malformations affecting the optic pathway are extremely rare.
Imran Jivraj; Michael Johnson
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