Results 91 to 100 of about 179,886 (315)

Vibration Deformation Measurement and Defect Identification Based on Time-Averaged Digital Holography

Photonics
Based on time-averaged digital holography, a vibration deformation measurement system was designed and a full process reconstruction and identification strategy was developed for detecting the micro-defects in optical materials.
Dongyang Hu, Chen Wang, Di Li, Weiyu Xu, Xiangchao Zhang   +4 more
doaj   +1 more source

All-optical photoacoustic microscopy

Photoacoustics, 2015
Three-dimensional photoacoustic microscopy (PAM) has gained considerable attention within the biomedical imaging community during the past decade. Detecting laser-induced photoacoustic waves by optical sensing techniques facilitates the idea of all ...
Sung-Liang Chen, L. Jay Guo, Xueding Wang   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Design of Environmental Biosensor Based on Photonic Crystal Fiber with Bends Using Finite Element Method [PDF]

, 2015
In this paper, a biosensor based on photonic crystal fiber (PCF) is proposed and designed using Full-Vectorial Finite Element Method (FVFEM). The proposed PCF sensor consists of three concentric circles surrounding the core.
Akowuah, Emmanuel Kofi, Dayoub, Iyad, Teyeb, A, Malek, FA, Malek, Fathi Abdel, Haxha, Shyqyri, Haxha, S, Teyeb, Ahmed, Akowuah, EK, Dayoub, I   +9 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Detecting ultrasound using optical fibres

, 2015
Optical fibre techniques for detecting ultrasonic waves are, in principle, well established. The ultrasonic wave could impose a pressure and/or strain field on an optical fibre in its path and this pressure and/or strain modulation would in turn be ...
Dong, Fengzhong, Thursby, Graham, Betz, Daniel, Park, Hee Su, Atique, Syed, Sorazu Lucio, Borja, Culshaw, Brian   +6 more
core   +1 more source

Super-resolution reconstruction for subsurface defects of optical elements based on CdSe/ZnS quantum dots fluorescence dichroism

AIP Advances
The subsurface defects (SSD) of optical elements have a significant impact on the service life and laser damage threshold of the inertial confinement nuclear fusion optical system. Due to the optical diffraction limit, fluorescence microscopy has limited
Rong Li, Chunyang Wang, Yajie Wu, Xuelian Liu, Yana Cui, Bo Xiao, Linzhe Deng   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Longitudinal optical binding

, 2008
Longitudinal optical binding refers to the light induced self organisation of micro particles in one dimension. In this thesis I will present experimental and theoretical studies of the separation between two dielectric spheres in a counter-propagating
Metzger, Nikolaus K.
core  

Detecting Vorticity in Optical Flow of Fluids

, 2010
This paper proposes a new physics-based approachfor processing optical flow characterizing the movementof fluids. The proposed method employs a robust solverbased on the Navier-Stokes equations defined by thefollowing processing stages: advection ...
Ashish Doshi, Adrian G. Bors, Doshi, A., Bors, A.   +3 more
core   +1 more source