Results 81 to 90 of about 498,908 (256)
A far-off-resonance optical trap for a Ba$^+$ ion
, 2014 Optical trapping and ions combine unique advantages of independently striving fields of research. Light fields can form versatile potential landscapes, such as optical lattices, for neutral and charged atoms, avoiding detrimental implications of ...
Huber, Thomas +4 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
PhotonicsBased on time-averaged digital holography, a vibration deformation measurement system was designed and a full process reconstruction and identification strategy was developed for detecting the micro-defects in optical materials.
Dongyang Hu +4 more
doaj +1 more source
All-optical photoacoustic microscopy
Photoacoustics, 2015 Three-dimensional photoacoustic microscopy (PAM) has gained considerable attention within the biomedical imaging community during the past decade. Detecting laser-induced photoacoustic waves by optical sensing techniques facilitates the idea of all ...
Sung-Liang Chen +2 more
doaj +1 more source
Narrowband spectroscopy by all-optical correlation of broadband pulses
, 2008 High peak power ultrafast lasers are widely used in nonlinear spectroscopy but often limit its spectral resolution because of the broad frequency bandwidth of ultrashort laser pulses. Improving the resolution by achieving spectrally narrow excitation of,
I. Pastirk +5 more
core +1 more source
Numerical method to optimize the Polar-Azimuthal Orientation of Infrared Superconducting Nanowire Single-Photon Detectors [PDF]
, 2011 A novel finite-element method for calculating the illumination-dependence of absorption in three-dimensional nanostructures is presented based on the RF module of the COMSOL software package.
Anant +11 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
AIP AdvancesThe subsurface defects (SSD) of optical elements have a significant impact on the service life and laser damage threshold of the inertial confinement nuclear fusion optical system. Due to the optical diffraction limit, fluorescence microscopy has limited
Rong Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source