Results 61 to 70 of about 498,908 (256)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Detecting Neutral Atoms on an Atom Chip [PDF]

, 2006
Detecting single atoms (qubits) is a key requirement for implementing quantum information processing on an atom chip. The detector should ideally be integrated on the chip.
Andrews, Armani, Berman, Cassettari, Denschlag, Duffy, Eriksson, Folman, Folman, Grimm, Haase, Henkel, Hommelhoff, Hope, Hope, Horak, Hänsel, Hänsel, Kadlecek, Key, Krüger, Leibfried, Lev, Liu, Long, Lye, Miller, Miroshnyenko, Moktadir, Müller, Ott, Pinkse, Reymond, Rosenblit, Saruwatari, Schlosser, Schlosser, Schneider, Schumm, Seidemann, Siegman, Turner, van Enk, van Enk, van Enk   +44 more
core   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A metalens for detecting fractional-order optical vortices

Компьютерная оптика
In this work, a metalens for detecting an incident field with a fractional topological charge ranging from – 2 to 0 is proposed. The metalens is based on a spiral zone plate with a topological charge of 1.5.
A.G. Nalimov, V.V. Kotlyar, Y.V. Khanenko, S.D. Poletaev   +3 more
doaj   +1 more source

Spot size measurements in the Eli-NP compton gamma source [PDF]

, 2016
A high brightness electron Linac is being built in the Compton Gamma Source at the ELI Nuclear Physics facility in Romania. To achieve the design luminosity, a train of 32 bunches with a nominal charge of 250 pC and 16 ns ...
Chiadroni, E., Cianchi, A., Cioeta, Fara, Di Pirro, G., Franzini, Giovanni, Marongiu, Marco, Mostacci, Andrea, Palumbo, Luigi, Shapakov, V., Stella, A., Variola, A.   +10 more
core  

Probing the extragalactic fast transient sky at minute timescales with DECam [PDF]

, 2019
Searches for optical transients are usually performed with a cadence of days to weeks, optimised for supernova discovery. The optical fast transient sky is still largely unexplored, with only a few surveys to date having placed meaningful constraints on ...
Abbott, Timothy M. C., Andreoni, Igor, Bhandari, Shivani, Caleb, Manisha, Chang, Seo-Won, Cooke, Jeffrey, Cucchiara, Antonino, Farah, Wael, Flynn, Christopher M., Jankowski, Fabian, Keane, Evan F., Lien, Amy, Moriya, Takashi J., Möller, Anais, Onken, Christopher, Parthasarathy, Aditya, Petroff, Emily, Price, Daniel C., Pritchard, Tyler A., Ravasio, Maria Edvige, Rest, Armin, Ryder, Stuart, Vohl, Dany, Webb, Sara, Wolf, Christian   +24 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Automatic detection of Cyanobacterial blooms using multi-source optical satellite imagery: method development and application

Ecological Indicators
Cyanobacterial blooms (CyanoBloom) are a widespread environmental concern in lakes, and optical satellite imagery has been widely used to monitor their spatiotemporal dynamics.
Hailong Zhang, Chen Lu, Deyong Sun, Xiaomin Ye, Shengqiang Wang, Quan Qin   +5 more
doaj   +1 more source

Moving Object Detection Using a Stereo Camera Mounted on a Moving Platform

SICE Journal of Control, Measurement, and System Integration, 2017
In this paper, we propose a method for detecting moving objects using a moving stereo camera. First, the camera motion parameters are estimated by using optical flow with a stereo camera.
Tetsuro Toda, Gakuto Masuyama, Kazunori Umeda   +2 more
doaj   +1 more source