Results 141 to 150 of about 1,291 (163)
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Quantitative analysis of GABAergic neurons in the mouse hippocampus, with optical disector using confocal laser scanning microscope

Brain Research, 1998
The numerical densities (NDs) of glutamic acid decarboxylase (GAD) 67 immunoreactive (IR) neurons in the mouse hippocampus were estimated according to the optical disector method using a confocal laser scanning microscope (CLSM), and the cell sizes of disector-counted neurons were measured.
S, Jinno, Y, Aika, T, Fukuda, T, Kosaka
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Estimate of the total number of neurons and glial and endothelial cells in the rat spinal cord by means of the optical disector

Journal of Comparative Neurology, 1993
AbstractThe total numbers of neurons and glial and endothelial cells in five rat spinal cords were estimated by stereological techniques.Each spinal cord was divided into 12 slabs of equal length. One transverse and one oblique slice was cut from each slab.
R, Bjugn, H J, Gundersen
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Colocalization of parvalbumin and somatostatin‐like immunoreactivity in the mouse hippocampus: Quantitative analysis with optical disector

The Journal of Comparative Neurology, 2000
The colocalization of parvalbumin (PV) and somatostatin (SS)-like immunoreactivity was studied quantitatively in the mouse hippocampus, with particular reference to their areal and dorsoventral differences. The optical disector method was applied by using a confocal laser scanning microscope with immunofluorescent double-labeling. In the present study,
S, Jinno, T, Kosaka
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Neuronal Cell Loss in the CA3 Subfield of the Hippocampus Following Cortical Contusion Utilizing the Optical Disector Method for Cell Counting

Journal of Neurotrauma, 1997
Unilateral cortical contusion in the rat results in cell loss in both the cortex and hippocampus. Pharmacological intervention with growth factors or excitatory neurotransmitter antagonists may reduce cell loss and improve neurological outcome. The window of opportunity for such intervention remains unclear because a detailed temporal analysis of ...
S A, Baldwin   +5 more
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Patterns of colocalization of neuronal nitric oxide synthase and somatostatin-like immunoreactivity in the mouse hippocampus: quantitative analysis with optical disector

Neuroscience, 2004
In some brain regions, previous studies reported the frequent coexistence between neuronal nitric oxide synthase (nNOS) and somatostatin (SOM). In the hippocampus, nNOS and SOM were mainly expressed in GABAergic nonprincipal neurons. Here we estimated the immunocytochemical colocalization of nNOS and SOM in the mouse hippocampus using the optical ...
S, Jinno, T, Kosaka
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The use of the optical disector to estimate the total number of neurons in the developing chick lateral motor column: Effects of purified growth factors

The Anatomical Record, 1991
AbstractCompetition between neurons for limited amounts of trophic factors is believed to be the basis for large‐scale neuronal death during the normal development of the vertebrate nervous system. In this study, an unbiased stereological counting method, an optical disector/Cavalieri combination, was used to estimate the total number of motor neurons ...
V, Nurcombe, N G, Wreford, J F, Bertram
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Total nerve cell number in neocortex in chronic schizophrenics and controls estimated using optical disectors

Biological Psychiatry, 1993
The total number of neurons was estimated in eight brains from chronic schizophrenic men and compared with 16 gender- and age-matched controls. The average total neocortical nerve cell number was 22.12.10(9) in schizophrenics and 22.06.10(9) in controls. The estimate of total cell numbers can not demonstrate more subtle neuronal losses of specific cell
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Two distinct events, section compression and loss of particles (“lost caps”), contribute to z‐axis distortion and bias in optical disector counting

Microscopy Research and Technique, 2006
AbstractDeformation of tissue sections in the z‐axis can bias optical disector counting. When samples of particle densities are not representative for the entire tissue section, significant bias of estimated numbers can result. To assess the occurrence, prevalence, extent, sequence of events, and causes of z‐axis distortion, the distribution of ...
Baryshnikova, Larisa M.   +3 more
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A brief update on physical and optical disector applications and sectioning-staining methods in neuroscience

2020
WOS ...
Yurt, Kiymet Kubra   +6 more
openaire   +1 more source

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