Results 131 to 140 of about 1,291 (163)
Current Protocols in Toxicology, 2000 AbstractThis unit describes techniques, based on recent advances in stereological methods, to obtain unbiased estimates of total cell or synapse number in discrete structures of the central nervous system. They combine unbiased counting frames, unbiased systematic random sampling, and unbiased estimates of the structure volume to produce the final ...
Jay S. Charleston
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Stereological Estimation of Neuronal Number: The Optical Disector/Cavalieri Combination
, 2003 Nurcombe, V. +2 more
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Journal of Microscopy, 1992
SUMMARYA description is given of a simple device, which, when attached to the fine adjustment vernier of a regular light microscope, alerts the operator by sound to the vertical distances travelled by the microscope stage without losing visual contact with the specimen.
Guy J. Laroye, William B. Taylor
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SUMMARYA description is given of a simple device, which, when attached to the fine adjustment vernier of a regular light microscope, alerts the operator by sound to the vertical distances travelled by the microscope stage without losing visual contact with the specimen.
Guy J. Laroye, William B. Taylor
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Estimation of the section thickness and optical disector height with a simple calibration method
Journal of Microscopy, 1998 McCrone
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The Journal of Comparative Neurology, 1999
Using a stereological method, the optical disector, we examined three inbred strains of mice (NZB/BINJ, DBA/2, and C57BL/6J) for morphological differences in volume, neuronal number, and density of the pyramidal cell and dentate gyrus granule cell layers of the hippocampus. We found significant differences in volume and neuronal number for both regions
I, Abusaad +5 more
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Using a stereological method, the optical disector, we examined three inbred strains of mice (NZB/BINJ, DBA/2, and C57BL/6J) for morphological differences in volume, neuronal number, and density of the pyramidal cell and dentate gyrus granule cell layers of the hippocampus. We found significant differences in volume and neuronal number for both regions
I, Abusaad +5 more
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The total number of neurons in the human neocortex unbiasedly estimated using optical disectors
Journal of Microscopy, 1990SUMMARYAn efficient method is presented for obtaining, in under 4h, an unbiased estimate of the total number of neurons in the human neocortex, with a coefficient of error on the estimate of ∼ 5%. The novel sampling scheme used in this study is unbiased and was designed so that only a small amount of neocortical grey matter had to be removed.
H, Braendgaard +3 more
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Proceedings, annual meeting, Electron Microscopy Society of America, 1993
Diabetic renal growth, regression and regrowth was studied using stereological methods on perfusion-fixed rat kidneys. A razor blade tissue slicer was used for cutting the entire kidney into 2-mm-thick slices and every second slice was sampled systematically random.
Nyengaard, Jens Randel +2 more
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Diabetic renal growth, regression and regrowth was studied using stereological methods on perfusion-fixed rat kidneys. A razor blade tissue slicer was used for cutting the entire kidney into 2-mm-thick slices and every second slice was sampled systematically random.
Nyengaard, Jens Randel +2 more
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The Journal of Comparative Neurology, 1999
A detailed quantitative analysis of immunocytochemically identified nonprincipal neurons containing neuronal nitric oxide synthase (nNOS) was performed on the mouse hippocampus, with particular reference to the dorsoventral gradient. The present study applied two variations of a stereologic technique, the optical disector--one that used confocal laser ...
S, Jinno, Y, Aika, T, Fukuda, T, Kosaka
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A detailed quantitative analysis of immunocytochemically identified nonprincipal neurons containing neuronal nitric oxide synthase (nNOS) was performed on the mouse hippocampus, with particular reference to the dorsoventral gradient. The present study applied two variations of a stereologic technique, the optical disector--one that used confocal laser ...
S, Jinno, Y, Aika, T, Fukuda, T, Kosaka
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Journal of Comparative Neurology, 2003
AbstractNeuropeptides are widely distributed in the central nervous system and are considered to play important roles in the regulation of neuronal activity. This study shows the patterns of expression of four neuropeptides [neuropeptide Y (NPY), somatostatin (SOM), cholecystokinin (CCK), and vasoactive intestinal polypeptide (VIP)] in γ‐aminobutyric ...
Shozo, Jinno, Toshio, Kosaka
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AbstractNeuropeptides are widely distributed in the central nervous system and are considered to play important roles in the regulation of neuronal activity. This study shows the patterns of expression of four neuropeptides [neuropeptide Y (NPY), somatostatin (SOM), cholecystokinin (CCK), and vasoactive intestinal polypeptide (VIP)] in γ‐aminobutyric ...
Shozo, Jinno, Toshio, Kosaka
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Total number of cancer cell nuclei and mitoses in breast tumors estimated by the optical disector.
Analytical and quantitative cytology and histology, 1997The total number of cancer cell nuclei, N(nuc), and of mitoses, N(mit), in the primary lesion are potentially important indicators of tumor biology. In the present study, such estimates were obtained on breast cancers by an unbiased stereologic method.The total number estimates are the product of two variables: (1) the volume of tumor, V(T), estimated ...
M, Ladekarl, V, Jensen, B, Nielsen
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