Results 31 to 40 of about 1,291 (163)

Parkinsonian beta oscillations in the external globus pallidus and their relationship with subthalamic nucleus activity [PDF]

, 2008
Inappropriately synchronized beta (β) oscillations (15–30 Hz) in the subthalamic nucleus (STN) accompany movement difficulties in idiopathic Parkinson's disease (PD).
Bolam, JP, L. F. Marton, Marton, LF, N. Mallet, P. J. Magill, J. P. Bolam, Mallet, N, Brown, Peter, A. Pogosyan, Pogosyan, A, Magill, PJ, Brown, P, P. Brown   +12 more
core   +1 more source

Postnatal Development of the Perirhinal and Parahippocampal Cortices: A Stereological Study in Macaque Monkeys

Journal of Comparative Neurology, Volume 534, Issue 1, January 2026.
Volumetric data reveal a late maturation of areas 36r and 36c compared to areas 35, TF, and TH, as well as a tendency for superficial layers in areas 36r and 36c to mature earlier than the deep layers. Neuronal soma size exhibits a transient increase at 6 months of age in most subdivisions.
Justine Villard, Loïc J. Chareyron, Pamela Banta Lavenex, David G. Amaral, Pierre Lavenex   +4 more
wiley   +1 more source

Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

, 2015
In neuroscience, the optical fractionator technique is frequently used for unbiased cell number estimations. Although unbiased in theory, the practical application of the technique is often biased by the necessity of introducing a guard zone at one side ...
Andersen, Stine Hasselholt, Lykkesfeldt, Jens, Larsen, Jytte Overgaard   +2 more
core   +1 more source

Streptozotocin‐Induced Diabetes Reduces Epididymal Sperm Storage More Than Testicular Sperm Production in Rats: A Stereological Finding

Andrologia, Volume 2026, Issue 1, 2026.
Previous studies showed considerable decrease of epididymal sperm count in diabetic rats and ascribed it to spermatogenic damage in the testis; diabetic rat models were therefore often used for pharmaceutical studies on sperm protection. But there were methodological problems with previous studies: sperm count obtained in many studies does not ...
Li Ma, Yu Xiang, Yang Guo, Xiao-Hong Wen, Yang-You Li, Bo Liao, Zheng-Wei Yang, Haney Samir   +7 more
wiley   +1 more source

Modulatory Effect of Lycopene and Ellagic Acid on Inflammatory Response in Cadmium Chloride–Induced Testicular Toxicity

Journal of Toxicology, Volume 2026, Issue 1, 2026.
Objective Testicle tissue is part of the genital system that may be destroyed by chemical materials such as cadmium chloride (Cd). Lycopene (Lyc) and ellagic acid (EA) can reduce the destructive effects of chemical materials. This study investigated lycopene and EA’s protective effects on Cd’s toxic effects on testis tissue in 18th‐day neonates during ...
Sanaz Jafari Barmak, Mehrzad Jafari Barmak, Jasbir Arora (RSS)   +2 more
wiley   +1 more source

Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model

Macromolecular Bioscience, Volume 25, Issue 7, July 2025.
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz, Aslihan Akalinli, Senem Buyuksungur, A. R. Cenk Celebi, Deniz Yucel, Nesrin Hasirci, Vasif Hasirci   +6 more
wiley   +1 more source

Dose‐related cardiac outcomes in response to postnatal dexamethasone treatment in premature lambs

The Anatomical Record, Volume 308, Issue 4, Page 1214-1228, April 2025.
Abstract Background Postnatal corticosteroids are used in the critical care of preterm infants for the prevention and treatment of bronchopulmonary dysplasia. We aimed to investigate the effects of early postnatal dexamethasone therapy and dose on cardiac maturation and morphology in preterm lambs.
Amanda Vrselja, Jennifer Jane Pillow, Jonathan G. Bensley, Siavash Ahmadi‐Noorbakhsh, Peter B. Noble, Mary Jane Black   +5 more
wiley   +1 more source

A Multiple Input Multiple Output Framework for the Automatic Optical Fractionator-based Cell Counting in Z-Stacks Using Deep Learning

, 2022
Quantifying cells in a defined region of biological tissue is critical for many clinical and preclinical studies, especially in pathology, toxicology, cancer, and behavior.
Dave, Palak
core  

Investigating the effects of rosmarinic acid on ovarian tissue, inflammatory markers, and sex hormones in polycystic ovary syndrome rats

Physiological Reports, Volume 13, Issue 7, April 2025.
Abstract Polycystic ovary syndrome (PCOS) causes the impairment of female fertility and elevates the risk of metabolic disorders. The current study aimed to evaluate the effects of rosmarinic acid (Ros) on the ovarian histo‐stereology, the level of reproductive hormones, and inflammation in a rat model of PCOS.
Sina Vakili, Farhad Koohpeyma, Mohammad Samare‐Najaf, Bahia Namavar Jahromi, Morteza Jafarinia, Sepide Goharitaban, Amir Savardashtaki, Ali Samareh, Fatemeh Amini, Mohammad Hashem Hashempur   +9 more
wiley   +1 more source

The Complexly Parcellated, Yet Quantitatively Reduced, Orexinergic/Hypocretinergic System of Humans

Journal of Comparative Neurology, Volume 533, Issue 2, February 2025.
Immunohistochemical staining for orexin‐A reveals the novel parvocellular orexinergic neuronal cluster (left) in the human brain. In comparison to the more typically observed orexinergic neurons of the main cluster (right), the parvocellular neurons have much smaller soma. Scale bar = 100 µm, applies to both images.
Illke B. Malungo, Ayanda Ngwenya, Mads F. Bertelsen, Muhammad A. Spocter, Thomas C. Thannickal, Jerome M. Siegel, Paul R. Manger   +6 more
wiley   +1 more source