Results 21 to 30 of about 1,291 (163)
Striatal injection of 6-hydroxydopamine induces retrograde degeneration and glial activation in the nigrostriatal pathway [PDF]
PURPOSE: The effect of a highly selective 6-hydroxydopamine (6-OHDA)-induced lesion of the nigrostriatal system on the astroglial and microglial activation was analysed in adult Wistar rats after an unilateral striatal injection of the neurotoxin ...
Ricardo Wilson Pinho Rodrigues +2 more
doaj +1 more source
The use of indirect measures of neuronal injury or neuroprotection, such as brain weight or the neuronal density of neurons, can lead to misinterpretations of biological processes.
Dorothy E Oorschot
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Abstract Immature neurons expressing the Bcl2 protein are present in various regions of the mammalian brain, including the amygdala and the entorhinal and perirhinal cortices. Their functional role is unknown but we have previously shown that neonatal and adult hippocampal lesions increase their differentiation in the monkey amygdala. Here, we assessed
Justine Villard +7 more
wiley +1 more source
UNBIASED STEREOLOGICAL ESTIMATION OF DIFFERENT CELL TYPES IN RAT CEREBRAL CORTEX
The total numbers of neurons, glial cells, and endothelial cells in rat cerebral cortex were estimated using unbiased stereological counting techniques and systematic sampling.
Maziar Davanlou, Donald F Smith
doaj +1 more source
Neurostereology Protocol for Unbiased Quantification of Neuronal Injury and Neurodegeneration
Neuronal injury and neurodegeneration are the hallmark pathologies in a variety of neurological conditions such as epilepsy, stroke, traumatic brain injury, Parkinson’s disease and Alzheimer’s disease.
Victoria M Golub +8 more
doaj +1 more source
In the last two decades, much light has been shed on hepatic fibrosis, and the activation / proliferation of Ito cells (IC) emerged to play a central role.
Ricardo Marcos +2 more
doaj +1 more source
Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]
It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Polgar, Erika +3 more
core +1 more source
Atherosclerosis is a chronic metabolic and inflammatory disease of vascular arteries. Insome cases, it comes the accumulation of the inflammatory cells and extracellular matrix in vessel intima, which lead to the narrowing of the vessel lumen. The aim of
Petr Nachtigal +5 more
doaj +1 more source
Changes in the number and size of oocytes can lead to fertilization problems. The present study aimed to evaluate the number, volume, and surface area of oocytes in healthy as well as nandrolone decanoate-treated (ND) mice using stereological methods ...
Saied Karbalay-Doust, Ali Noorafshan
doaj +1 more source
The optical fractionator sampling scheme.
A hemisphere was randomly selected and sectioned into 100 µm-thick coronal sections, from which a predetermined fraction, the section sampling fraction (ssf), was systematically (sampled sections were separated by an equal distance) and randomly (the ...
Jack Hou (311665) +2 more
core +1 more source

