Results 41 to 50 of about 1,291 (163)

Disrupted dopamine transmission and the emergence of exaggerated beta oscillations in subthalamic nucleus and cerebral cortex

, 2008
In the subthalamic nucleus (STN) of Parkinson’s disease (PD) patients, a pronounced synchronization of oscillatory activity at beta frequencies (15–30 Hz) accompanies movement difficulties.
Sharott, A, Brown, Peter, Bolam, JP, Pogosyan, A, Magill, PJ, Brown, P, Mallet, N, Csicsvari, J   +7 more
core   +1 more source

The Ameliorative Effects of Probiotics on the Sperm Quality and Testicular Structure After Ischemia/Reperfusion Injury Following Testicular Torsion/Detorsion

Andrologia, Volume 2025, Issue 1, 2025.
Oxidative stress is a critical contributor to the pathophysiology of ischemia/reperfusion (I/R) injury associated with testicular torsion (TT) and detorsion (D) (TT/D). This study examines the antioxidative properties of the probiotics Lactobacillus (L.) reuteri and Lactobacillus (L.) rhamnosus in ameliorating TT/D‐induced oxidative and histological ...
Zohresadat Akbari, Narges Karbalaei, Saied Karbalay-Doust, Seyed Shahram Shekarforoush, Farhad Koohpeyma, Sourena Rastin, Larbi Allai   +6 more
wiley   +1 more source

Stereological Analysis of the Rhesus Monkey Perirhinal and Parahippocampal Cortices

Journal of Comparative Neurology, Volume 532, Issue 11, November 2024.
•The laminar organization of the monkey perirhinal and parahippocampal cortices supports the view that high‐order association cortices are characterized by relatively large superficial layers, with larger neurons and a lower neuronal density. •Species differences in the relative size and number of neurons in these areas indicate a greater relative ...
Justine Villard, Loïc J. Chareyron, Pamela Banta Lavenex, David G. Amaral, Pierre Lavenex   +4 more
wiley   +1 more source

Thyroid hormone analogues: Promising therapeutic avenues to improve the neurodevelopmental outcomes of intrauterine growth restriction

Journal of Neurochemistry, Volume 168, Issue 9, Page 2335-2350, September 2024.
Intrauterine growth restriction (IUGR) is a condition that adversely impacts brain development, predisposing an infant to neurodevelopmental deficits, including lasting learning, cognitive and motor deficits. IUGR results in a significant impairment of cerebral thyroid hormone signalling, integral to the development of white and grey matter.
Ginevra Chincarini, David W. Walker, Flora Wong, Samantha J. Richardson, Angela Cumberland, Mary Tolcos   +5 more
wiley   +1 more source

Counting particles in tissue sections: Choices of methods and importance of calibration to minimize biases [PDF]

, 2002
Investigators must choose between counting methods to quantify microscopic particles in tissues. The c o nventional profile-based ("model-based" or "2D-") counting methods have been criticized for their potential biases due to assumptions about ...
von Bartheld, C.S.
core  

Stereological Assessment of PC Density.

, 2014
This figure depicts our stereological approach for quantifying PC density in each region of the cerebellum. 2a displays a full sagittal section of the human brain.
Jerry Skefos (526825), Katrina Weed (526828), Christopher Cummings (213440), Ezra Levy (526829), Tarik Yuce (526830), Jarrod Holiday (526827), Thomas Kemper (526831), Margaret Bauman (526832), Katelyn Enzer (526826)   +8 more
core   +1 more source

Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease

Alzheimer's &Dementia, Volume 20, Issue 8, Page 5198-5219, August 2024.
Abstract INTRODUCTION The understanding of the pathological events in Alzheimer's disease (AD) has advanced dramatically, but the successful translation from rodent models into efficient human therapies is still problematic. METHODS To examine how tau pathology can develop in the primate brain, we injected 12 macaques with a dual tau mutation (P301L ...
Danielle Beckman, Giovanne B. Diniz, Sean Ott, Brad Hobson, Abhijit J. Chaudhari, Scott Muller, Yaping Chu, Akihiro Takano, Adam J. Schwarz, Chien‐Lin Yeh, Paul McQuade, Paramita Chakrabarty, Nicholas M. Kanaan, Maria S. Quinton, Arthur A. Simen, Jeffrey H. Kordower, John H. Morrison   +16 more
wiley   +1 more source

Nuclear parcellation and numbers of orexinergic neurons in five species of larger brained birds

Journal of Comparative Neurology, Volume 532, Issue 3, March 2024.
Immunohistochemical staining for orexin‐A reveals the orexinergic neuronal population in the hypothalamus of the Congo gray parrot. The arrangement of orexinergic neurons in the avian hypothalamus shows distinct conservation across avian species, unlike the variance noted in mammals. Abstract The orexinergic/hypocretinergic system, while having several
Pedzisai Mazengenya, Muhammad A. Spocter, Paul R. Manger   +2 more
wiley   +1 more source

Cell density and cortical thickness in Heschl's gyrus in schizophrenia, major depression and bipolar disorder

, 2004
There is evidence that the superior temporal gyrus and Heschl's gyrus within it are implicated in schizophrenia. We investigated neuronal and glial cell density and cortical thickness within Heschl's gyrus, using the optical disector to estimate cell ...
Cotter, D, Frangou, S, Mackay, D, Hudson, L, Landau, S; id_orcid   +4 more
core   +1 more source

The last stage of development: The restructuring and plasticity of the cortex during adolescence especially at puberty

Developmental Psychobiology, Volume 66, Issue 2, February 2024.
Abstract There is considerable evidence of reorganization in the prefrontal cortex during adolescence in humans, as well as in rodents, where the cellular basis can be explored. Studies from my laboratory in the rat medial prefrontal cortex are reviewed here. In general, growth predominates before puberty.
Janice M. Juraska
wiley   +1 more source