Results 231 to 240 of about 99,235 (279)

Exploration of Neurodegenerative Diseases Using Long-Read Sequencing and Optical Genome Mapping Technologies. [PDF]

Mov Disord
Cogan G, Daida K, Blauwendraat C, Billingsley K, Brice A.   +4 more
europepmc   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Optical Genome Mapping for Cryptic Chromosomal Rearrangements Identification in Clinical Practice

Maternal-Fetal Medicine
Chunxiang Zhou, Honglei Duan, Linlin He, Huijun Li, Yiyan Shi, Jie Li, Yang Pan, Jue Li   +7 more
doaj   +1 more source

Optical genome mapping identifies novel ENOX2::RUNX1 t(X;21)(q26.1;q22.12) rearrangement in acute myeloid leukemia-myelodysplasia related: first case report. [PDF]

Mol Cytogenet
George GV, Ali S, Syposs CR, Iqbal MA.
europepmc   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Optical genome mapping enhances cytogenetic analysis in recurrent miscarriage: confirmation of a suspected (1;10) chromosomal translocation. [PDF]

Mol Cytogenet
Del Águila MDM, Bernal M, Vílchez JR, Romero B, Castilla JA, Álvarez G, Clavero A, Poyatos A, Ruíz-Cabello F.   +8 more
europepmc   +1 more source

Clinical Utility of Optical Genome Mapping as an Additional Tool in a Standard Cytogenetic Workup in Hematological Malignancies. [PDF]

Cancers (Basel)
Toruner GA, Hu S, Loghavi S, Ok CY, Tang Z, Wei Q, Kanagal-Shamanna R, Medeiros LJ, Tang G.   +8 more
europepmc   +1 more source

Exploring the Potential of Optical Genome Mapping in the Diagnosis and Prognosis of Soft Tissue and Bone Tumors. [PDF]

Int J Mol Sci
Berenguer-Rubio A, Such E, Hernández NT, González-Rojo P, Díaz-González Á, Avetisyan G, Gil-Aparicio C, González-López J, Pantoja-Borja N, Rubio-Martínez LA, Hernández-Girón S, Valera-Cuesta MS, Ramírez-Fuentes C, Simonet-Redondo M, Díaz-Beveridge R, de la Calva C, Amaya-Valero JV, Ballester-Ibáñez C, Liquori A, Giner F, Mayordomo-Aranda E.   +20 more
europepmc   +1 more source

Unveiling the Complexity of KMT2A Rearrangements in Acute Myeloid Leukemias with Optical Genome Mapping. [PDF]

Cancers (Basel)
Lacoste SA, Gagnon V, Béliveau F, Lavallée S, Collin V, Hébert J.   +5 more
europepmc   +1 more source

Retrospective study on the utility of optical genome mapping as a follow-up method in genetic diagnostics. [PDF]

J Med Genet
Dremsek P, Schachner A, Reischer T, Krampl-Bettelheim E, Bettelheim D, Vrabel S, Delissen Z, Pfeifer M, Weil B, Bajtela R, Hengstschläger M, Laccone F, Neesen J.   +12 more
europepmc   +1 more source