Optical imaging of metabolic dynamics in animals
Direct visualization of metabolic dynamics in living animals with high spatial and temporal resolution is essential to understanding many biological processes. Here we introduce a platform that combines deuterium oxide (D2O) probing with stimulated Raman
Lingyan Shi +10 more
semanticscholar +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Near-Infrared Optical Imaging of Necrotic Cells by Photostable Lanthanide-Based Metallacrowns.
Sensitive detection of cell necrosis is crucial for the determination of cell viability. Because of its high resolution at the cellular level and sensitivity, optical imaging is highly attractive for identifying cell necrosis.
I. Martinić +4 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Phase-Intensity Surface Plasmon Resonance Biosensor for Avian Influenza A (H5N1) Detection
In this paper, we present a phase-intensity surface plasmon resonance (SPR) biosensor and demonstrate its use for avian influenza A (H5N1) antibody biomarker detection.
Chi Lok Wong +5 more
doaj +1 more source
Super-multiplexed optical imaging and barcoding with engineered polyynes
Optical multiplexing has a large impact in photonics, the life sciences and biomedicine. However, current technology is limited by a 'multiplexing ceiling' from existing optical materials. Here we engineered a class of polyyne-based materials for optical
Fanghao Hu +6 more
semanticscholar +1 more source
Lensless ultrafast optical imaging
AbstractLensless single-shot ultrafast optical imaging is realized by integrating an acousto-optic programmable dispersive filter with spectrally filtered sequentially time all-optical mapping photography, which enables independent control of frame rate, frame intensity, and exposure time with a simple system design.
Jian Zhao, Mingsheng Li
openaire +3 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Motionless volumetric photoacoustic microscopy with spatially invariant resolution
Photoacoustic microscopy allows for label-free 3D in vivo imaging by detecting the acoustic response of a photoexcited material. Here, Yang et. al use a digital-micromirror-device based structured illumination scheme to both improve resolution and ...
Jiamiao Yang +6 more
doaj +1 more source
Multilayer Cascade Screening Strategy for Semi-Supervised Change Detection in Hyperspectral Images
Change detection (CD) is an important application of remote sensing, which provides information about land cover changes on the Earth's surface.
Lian Liu +3 more
doaj +1 more source

