Results 51 to 60 of about 8,813,709 (334)

Optical imaging of metabolic dynamics in animals

open access: yesNature Communications, 2018
Direct visualization of metabolic dynamics in living animals with high spatial and temporal resolution is essential to understanding many biological processes. Here we introduce a platform that combines deuterium oxide (D2O) probing with stimulated Raman
Lingyan Shi   +10 more
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Near-Infrared Optical Imaging of Necrotic Cells by Photostable Lanthanide-Based Metallacrowns.

open access: yesJournal of the American Chemical Society, 2017
Sensitive detection of cell necrosis is crucial for the determination of cell viability. Because of its high resolution at the cellular level and sensitivity, optical imaging is highly attractive for identifying cell necrosis.
I. Martinić   +4 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Phase-Intensity Surface Plasmon Resonance Biosensor for Avian Influenza A (H5N1) Detection

open access: yesSensors, 2017
In this paper, we present a phase-intensity surface plasmon resonance (SPR) biosensor and demonstrate its use for avian influenza A (H5N1) antibody biomarker detection.
Chi Lok Wong   +5 more
doaj   +1 more source

Super-multiplexed optical imaging and barcoding with engineered polyynes

open access: yesNature Methods, 2017
Optical multiplexing has a large impact in photonics, the life sciences and biomedicine. However, current technology is limited by a 'multiplexing ceiling' from existing optical materials. Here we engineered a class of polyyne-based materials for optical
Fanghao Hu   +6 more
semanticscholar   +1 more source

Lensless ultrafast optical imaging

open access: yesLight: Science & Applications, 2022
AbstractLensless single-shot ultrafast optical imaging is realized by integrating an acousto-optic programmable dispersive filter with spectrally filtered sequentially time all-optical mapping photography, which enables independent control of frame rate, frame intensity, and exposure time with a simple system design.
Jian Zhao, Mingsheng Li
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Motionless volumetric photoacoustic microscopy with spatially invariant resolution

open access: yesNature Communications, 2017
Photoacoustic microscopy allows for label-free 3D in vivo imaging by detecting the acoustic response of a photoexcited material. Here, Yang et. al use a digital-micromirror-device based structured illumination scheme to both improve resolution and ...
Jiamiao Yang   +6 more
doaj   +1 more source

Multilayer Cascade Screening Strategy for Semi-Supervised Change Detection in Hyperspectral Images

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022
Change detection (CD) is an important application of remote sensing, which provides information about land cover changes on the Earth's surface.
Lian Liu   +3 more
doaj   +1 more source

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