Results 71 to 80 of about 346,176 (326)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Using Higher Diffraction Orders to Improve the Accuracy and Robustness of Overlay Measurements

Micromachines
This paper introduces a method for improving the measurement performance of single wavelength overlay errors by incorporating higher diffraction orders. In this method, to enhance the accuracy and robustness of overlay error detection between layers, the
Shaoyu Liu, Yan Tang, Xiaolong Cheng, Yuliang Long, Jinfeng Jiang, Yu He, Lixin Zhao   +6 more
doaj   +1 more source

Orbital angular momentum 25 years on [invited] [PDF]

, 2017
Twenty-five years ago Allen, Beijersbergen, Spreeuw, and Woerdman published their seminal paper establishing that light beams with helical phase-fronts carried an orbital angular momentum. Previously orbital angular momentum had been associated only with
Padgett, Miles J.
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

A Hierarchical Inverse Lithography Method Considering the Optimization and Manufacturability Limit by Gradient Descent

Micromachines
Inverse lithography technology (ILT) based on the gradient descent (GD) algorithm, which is a classical local optimal method, can effectively improve the lithographic imaging fidelity.
Haifeng Sun, Qingyan Zhang, Jie Zhou, Jianwen Gong, Chuan Jin, Ji Zhou, Junbo Liu   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Berry phase of light Bragg-reflected by chiral liquid crystal media [PDF]

, 2016
Berry phase is revealed for circularly polarized light when it is Bragg-reflected by a chiral liquid crystal medium of the same handedness. By using a chiral nematic layer we demonstrate that if the input plane of the layer is rotated with respect to a ...
Barboza, Raouf, Bortolozzo, Umberto, Clerc, Marcel G., Residori, Stefania   +3 more
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Free-form catenary-inspired meta-couplers for ultra-high or broadband vertical coupling

Nanophotonics
Metasurface-assisted waveguide couplers, or meta-couplers, innovatively link free-space optics with on-chip devices, offering flexibility for polarization and wavelength (de)multiplexing, mode-selective coupling, and guided mode manipulation.
Chen Tianqu, Xu Mingfeng, Pu Mingbo, Tang Xi, Zheng Yuhan, Zeng Qingji, Xiao Yuting, Ha Yingli, Guo Yinghui, Zhang Fei, Chi Nan, Luo Xiangang   +11 more
doaj   +1 more source