Results 61 to 70 of about 345,999 (291)

Brownian Motion in a Speckle Light Field: Tunable Anomalous Diffusion and Deterministic Optical Manipulation [PDF]

, 2013
The motion of particles in random potentials occurs in several natural phenomena ranging from the mobility of organelles within a biological cell to the diffusion of stars within a galaxy.
Gigan, Sylvain, Volpe, Giorgio, Volpe, Giovanni   +2 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Dynamic nonlocal metasurface for multifunctional integration via phase-change materials

Nanophotonics
Non-local metasurface supporting geometric phases at bound states in the continuum (BIC) simultaneously enables sharp spectral resonances and spatial wavefront shaping, thus providing a diversified optical platform for multifunctional devices. However, a
Yu Shilin, Xu Mingfeng, Pu Mingbo, Tang Xi, Zheng Yuhan, Guo Yinghui, Zhang Fei, Li Xiong, Ma Xiaoliang, Luo Xiangang   +9 more
doaj   +1 more source

Optimal control of atom transport for quantum gates in optical lattices [PDF]

, 2008
By means of optimal control techniques we model and optimize the manipulation of the external quantum state (center-of-mass motion) of atoms trapped in adjustable optical potentials. We consider in detail the cases of both non interacting and interacting
B. L. Brown, E. Anderson, G. De Chiara, J. V. Porto, J. W. Thomas, M. Anderlini, M. Shapiro, P. J. Lee, S. A. Rice, S. Montangero, T. Calarco, V. F. Krotov, W. D. Phillips   +12 more
core   +2 more sources

Cell stimulation with optically manipulated microsources [PDF]

Nature Methods, 2009
Molecular gradients are important for various biological processes including the polarization of tissues and cells during embryogenesis and chemotaxis. Investigations of these phenomena require control over the chemical microenvironment of cells. We present a technique to set up molecular concentration patterns that are chemically, spatially and ...
Holger, Kress, Jin-Gyu, Park, Cecile O, Mejean, Jason D, Forster, Jason, Park, Spencer S, Walse, Yong, Zhang, Dianqing, Wu, Orion D, Weiner, Tarek M, Fahmy, Eric R, Dufresne   +10 more
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A Hierarchical Inverse Lithography Method Considering the Optimization and Manufacturability Limit by Gradient Descent

Micromachines
Inverse lithography technology (ILT) based on the gradient descent (GD) algorithm, which is a classical local optimal method, can effectively improve the lithographic imaging fidelity.
Haifeng Sun, Qingyan Zhang, Jie Zhou, Jianwen Gong, Chuan Jin, Ji Zhou, Junbo Liu   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Influence of Lithography Process Parameters on Continuous Surface Diffractive Optical Elements for Laser Beam Shaping

Micromachines
To address the demand for laser beam-shaping techniques, we developed a one-step exposure process based on moving-mask lithography for the fabrication of a continuous-surface diffractive optical element (DOE) for laser beam shaping.
Wenjing Liu, Axiu Cao, Junbo Liu, Hui Pang, Qiling Deng, Jian Wang, Song Hu   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source