Optical mapping of contracting hearts. [PDF]
J Physiol, 2023 Optical mapping is a widely used tool to record and visualize the electrophysiological properties in a variety of myocardial preparations such as Langendorff‐perfused isolated hearts, coronary‐perfused wedge preparations, and cell culture monolayers ...
Kappadan V +8 more
europepmc +9 more sources
Tunable nonlinear optical mapping in a multiple-scattering cavity. [PDF]
Proc Natl Acad Sci U S A, 2023 Significance Nonlinear optics has a wide range of applications but requires high optical power. We propose and demonstrate an unconventional type of nonlinear mapping of a linear random-scattering cavity, based on nonlinear relation between optical ...
Eliezer Y +4 more
europepmc +2 more sources
Optical Mapping of Cardiomyocytes in Monolayer Derived from Induced Pluripotent Stem Cells. [PDF]
Cells, 2023 Optical mapping is a powerful imaging technique widely adopted to measure membrane potential changes and intracellular Ca2+ variations in excitable tissues using voltage-sensitive dyes and Ca2+ indicators, respectively.
Djemai M +3 more
europepmc +2 more sources
Optical mapping compendium of structural variants across global cattle breeds. [PDF]
Sci Data, 2022 Structural variants (SV) have been linked to important bovine disease phenotypes, but due to the difficulty of their accurate detection with standard sequencing approaches, their role in shaping important traits across cattle breeds is largely unexplored.
Talenti A +18 more
europepmc +3 more sources
A comprehensive framework for evaluation of high pacing frequency and arrhythmic optical mapping signals [PDF]
Frontiers in Physiology, 2023 Introduction: High pacing frequency or irregular activity due to arrhythmia produces complex optical mapping signals and challenges for processing.
Girish S. Ramlugun +16 more
doaj +2 more sources
High resolution optical mapping of cardiac electrophysiology in pre-clinical models. [PDF]
Sci Data, 2022 Optical mapping of animal models is a widely used technique in pre-clinical cardiac research. It has several advantages over other methods, including higher spatial resolution, contactless recording and direct visualisation of action potentials and ...
O'Shea C +13 more
europepmc +2 more sources
Real-Time Optical Mapping of Contracting Cardiac Tissues With GPU-Accelerated Numerical Motion Tracking. [PDF]
Front Cardiovasc Med, 2022 Optical mapping of action potentials or calcium transients in contracting cardiac tissues are challenging because of the severe sensitivity of the measurements to motion.
Lebert J, Ravi N, Kensah G, Christoph J.
europepmc +2 more sources
Optical mapping and optogenetics in cardiac electrophysiology research and therapy: a state-of-the-art review. [PDF]
EuropaceState-of-the-art innovations in optical cardiac electrophysiology are significantly enhancing cardiac research. A potential leap into patient care is now on the horizon.
Baines O +6 more
europepmc +2 more sources
Advances in optical mapping for genomic research
Computational and Structural Biotechnology Journal, 2020 Recent advances in optical mapping have allowed the construction of improved genome assemblies with greater contiguity. Optical mapping also enables genome comparison and identification of large-scale structural variations.
Yuxuan Yuan +2 more
doaj +2 more sources
COSMAS: a lightweight toolbox for cardiac optical mapping analysis. [PDF]
Sci Rep, 2021 Optical mapping is widely used in experimental cardiology, as it allows visualization of cardiac membrane potential and calcium transients. However, optical mapping measurements from a single heart or cell culture can produce several gigabytes of data ...
Tomek J +4 more
europepmc +2 more sources