Results 21 to 30 of about 3,449,089 (306)

Optical mapping as a routine tool for bacterial genome sequence finishing [PDF]

, 2007
Background: In sequencing the genomes of two Xenorhabdus species, we encountered a large number of sequence repeats and assembly anomalies that stalled finishing efforts.
Norton, S., Miller, N., Zijin Du, Goldman, Barry S., Latreille Phil, Bode, Helge Björn, Henkhaus John, Forst, Steve, John Henkhaus, Goodrich-Blair, H., Miller, Nancy, Slater Steven, Stacie Norton, Bode, H., Goldman Barry S, Henkhaus, J., Gaudriault, S., Steve Forst, Creg Darby, Gaudriault Sophie, Darby Creg, Goldman, B., Gaudriault, Sophie, Darby, C., Du, Z., Goodner, B., Norton, Stacie, Sophie Gaudriault, Miller Nancy, Goodrich-Blair, Heidi, Henkhaus, John, Heidi Goodrich-Blair, Gaudriault, Sophie, S., Latreille, Phil, Slater, S., Goodrich-Blair Heidi, Goodner, Brad, Goodner Brad, Latreille, P., Bode, Helge B., Nancy Miller, Norton Stacie, Brad Barbazuk, Phil Latreille, Steven Slater, Slater, Steven, Forst Steve, Helge B Bode, Forst, S., Barbazuk, Brad, Barbazuk Brad, Du, Zijin, Bode Helge B, Barry S Goldman, Du Zijin, Brad Goodner, Barbazuk, B., Darby, Creg   +57 more
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Electromechanical optical mapping

Progress in Biophysics and Molecular Biology, 2017
Optical mapping is a widely used imaging technique for investigating cardiac electrophysiology in intact, Langendorff-perfused hearts. Mechanical contraction of cardiac tissue, however, may result in severe motion artifacts and significant distortion of the fluorescence signals.
Christoph, J., Schröder-Schetelig, J., Luther, Stefan   +2 more
openaire   +4 more sources

Optical Mapping of Cardiac Electromechanics [PDF]

Biophysical Journal, 2016
Cardiac biophysics rests on three fundamental pillars: energy production, electrical excitation, and mechanical work. Studies of cardiac metabolism, bioelectricity, and biomechanics have been very productive at all levels of reduced complexity, but especially at the levels of tissue, cell, and molecule.
Matthew W, Kay, Igor R, Efimov
openaire   +2 more sources

Effects of pacing site and stimulation history on alternans dynamics and the development of complex spatiotemporal patterns in cardiac tissue

Frontiers in Physiology, 2013
Alternans of action potential duration has been associated with T-wave alternans and the development of arrhythmias because it produces large gradients of repolarization. However, little is known about alternans dynamics in large mammalian hearts.
Alessio eGizzi, Elizabeth eCherry, Robert F Gilmour, Stefan eLuther, Simonetta eFilippi, Flavio H Fenton   +5 more
doaj   +1 more source

Optogenetic Control of Human Induced Pluripotent Stem Cell‐Derived Cardiac Tissue Models

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Optogenetics, using light‐sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high‐resolution optogenetic approaches to modulate electrical activity in 2‐ and 3‐dimensional ...
Amit Gruber, Oded Edri, Shany Glatstein, Idit Goldfracht, Irit Huber, Gil Arbel, Amira Gepstein, Snizhanna Chorna, Lior Gepstein   +8 more
doaj   +1 more source

Refinement of optical map assemblies [PDF]

Bioinformatics, 2006
Abstract Motivation: Genomic mutations and variations provide insightful information about the functionality of sequence elements and their association with human diseases. Traditionally, variations are identified through analysis of short DNA sequences, usually shorter than 1000 bp per fragment. Optical maps provide both faster and more
Anton Valouev, Yu Zhang 0002, David C. Schwartz, Michael S. Waterman   +3 more
openaire   +3 more sources

Image processing for optical mapping [PDF]

GigaScience, 2015
Optical Mapping is an established single-molecule, whole-genome analysis system, which has been used to gain a comprehensive understanding of genomic structure and to study structural variation of complex genomes. A critical component of Optical Mapping system is the image processing module, which extracts single molecule restriction maps from image ...
Ravindran, Prabu, Gupta, Aditya
openaire   +2 more sources

Billa Kalina [cartographic material] /

, 1948
Topographic map of Billa Kalina, South Australia. Relief shown by spot heights.; On verso: Mis.13079.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. National Mapping Section.
core   +3 more sources

Broadband Backhaul Communication for Stratospheric Platforms: The Stratospheric Optical Payload Experiment (STROPEX) [PDF]

, 2006
A high bitrate optical downlink was performed by the stratospheric optical payload experiment (STROPEX), a part of the EU CAPANINA project. The STROPEX objectives were to design and build the necessary hardware to demonstrate an optical backhaul downlink
Knapek, Markus, Markus Knapek, Martin Brechtelsbauer, Joachim Horwath, Horwath, Joachim, Wilkerson, Brandon, Brandon Wilkerson, Brechtelsbauer, Martin, Bernhard Epple, Epple, Bernhard   +9 more
core   +1 more source

Examination of the Effects of Conduction Slowing on the Upstroke of Optically Recorded Action Potentials

Frontiers in Physiology, 2019
IntroductionThe upstroke of optical action potentials (APs) recorded from intact hearts are generally recognized to be slower than those recorded with microelectrodes.
Christopher O’Shea, Christopher O’Shea, Davor Pavlovic, Kashif Rajpoot, James Winter   +4 more
doaj   +1 more source