Results 21 to 30 of about 581,508 (291)
CCD-based imaging and 3D space--time mapping of terahertz fields via Kerr frequency conversion [PDF]
We investigate the spatially and temporally resolved four-wave mixing of terahertz (THz) fields and optical pulses in large-bandgap dielectrics, such as diamond. We show that it is possible to perform beam profiling and space–time resolved mapping of THz
Chan +25 more
core +1 more source
Electromechanical optical mapping
Optical mapping is a widely used imaging technique for investigating cardiac electrophysiology in intact, Langendorff-perfused hearts. Mechanical contraction of cardiac tissue, however, may result in severe motion artifacts and significant distortion of the fluorescence signals.
Christoph, J. +2 more
openaire +4 more sources
Image processing for optical mapping [PDF]
Optical Mapping is an established single-molecule, whole-genome analysis system, which has been used to gain a comprehensive understanding of genomic structure and to study structural variation of complex genomes. A critical component of Optical Mapping system is the image processing module, which extracts single molecule restriction maps from image ...
Ravindran, Prabu, Gupta, Aditya
openaire +2 more sources
Optogenetic Control of Human Induced Pluripotent Stem Cell‐Derived Cardiac Tissue Models
Background Optogenetics, using light‐sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high‐resolution optogenetic approaches to modulate electrical activity in 2‐ and 3‐dimensional ...
Amit Gruber +8 more
doaj +1 more source
Refinement of optical map assemblies [PDF]
Abstract Motivation: Genomic mutations and variations provide insightful information about the functionality of sequence elements and their association with human diseases. Traditionally, variations are identified through analysis of short DNA sequences, usually shorter than 1000 bp per fragment. Optical maps provide both faster and more
Anton Valouev +3 more
openaire +2 more sources
IntroductionThe upstroke of optical action potentials (APs) recorded from intact hearts are generally recognized to be slower than those recorded with microelectrodes.
Christopher O’Shea +4 more
doaj +1 more source
Service-Oriented Multigranular Optical Network Architecture for Clouds [PDF]
This paper presents a novel service-oriented network architecture to bridge the informational gap between user applications and optical networks providing technology-agnostic multigranular optical network services for clouds.
Abosi +20 more
core +1 more source
Optical Mapping of Cardiac Electromechanics [PDF]
Cardiac biophysics rests on three fundamental pillars: energy production, electrical excitation, and mechanical work. Studies of cardiac metabolism, bioelectricity, and biomechanics have been very productive at all levels of reduced complexity, but especially at the levels of tissue, cell, and molecule.
Matthew W, Kay, Igor R, Efimov
openaire +2 more sources
Light scattering during optical imaging of electrical activation within the heart is known to significantlydistort the optically-recorded action potential (AP) upstroke, as well as affecting the magnitude of the measured response of ventricular tissue to
Martin J Bishop, Gernot ePlank
doaj +1 more source
Probing the Electrophysiology of the Developing Heart
Many diseases that result in dysfunction and dysmorphology of the heart originate in the embryo. However, the embryonic heart presents a challenging subject for study: especially challenging is its electrophysiology.
Michiko Watanabe +5 more
doaj +1 more source

