Results 91 to 100 of about 4,290,469 (326)

Antiarrhythmic Properties of Elsholtzia ciliata Essential Oil on Electrical Activity of the Isolated Rabbit Heart and Preferential Inhibition of Sodium Conductance

open access: yesBiomolecules, 2020
Elsholtzia ciliata essential oil (E. ciliata) has been developed in Lithuania and internationally patented as exerting antiarrhythmic properties. Here we demonstrate the pharmacological effects of this herbal preparation on cardiac electrical activity ...
Regina Mačianskienė   +7 more
doaj   +1 more source

EP-PINNs: Cardiac Electrophysiology Characterisation Using Physics-Informed Neural Networks

open access: yesFrontiers in Cardiovascular Medicine, 2022
Accurately inferring underlying electrophysiological (EP) tissue properties from action potential recordings is expected to be clinically useful in the diagnosis and treatment of arrhythmias such as atrial fibrillation.
Clara Herrero Martin   +7 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis

open access: yesJournal of Cardiovascular Development and Disease, 2022
The cardiac conduction system, a network of specialized cells, is required for the functioning of the heart. The basic helix loop helix factors Hand1 and Hand2 are required for cardiac morphogenesis and have been implicated in cardiac conduction system ...
Rajani M. George   +4 more
doaj   +1 more source

Magnetic-induced phonon anisotropy in ZnCr$_2$O$_4$ from first principles

open access: yes, 2006
We have studied the influence of magnetic order on the optical phonons of the geometrically frustrated spinel ZnCr$_2$O$_4$ from first-principles. By mapping the first-principles phonon calculations onto a Heisenberg-like model, we developed a method to ...
Craig J. Fennie   +3 more
core   +1 more source

Determining the HI content of galaxies via intensity mapping cross-correlations [PDF]

open access: yes, 2017
We propose an innovative method for measuring the neutral hydrogen (HI) content of an optically-selected spectroscopic sample of galaxies through cross-correlation with HI intensity mapping measurements.
Blake, C., Wolz, L., Wyithe, J. S. B.
core   +2 more sources

Clinical application of single‐molecule optical mapping to a multigeneration FSHD1 pedigree

open access: yesMolecular Genetics & Genomic Medicine, 2019
Facioscapulohumeral muscular dystrophy 1 (FSHD1) is a relatively common autosomal dominant adult muscular dystrophy with variable disease penetrance. The disease is caused by shortening of a D4Z4 repeat array located near the telomere of chromosome 4 at ...
Qian Zhang   +10 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Optical Electrophysiology in the Developing Heart

open access: yesJournal of Cardiovascular Development and Disease, 2018
The heart is the first organ system to form in the embryo. Over the course of development, cardiomyocytes with differing morphogenetic, molecular, and physiological characteristics are specified and differentiate and integrate with one another to ...
Kandace Thomas   +3 more
doaj   +1 more source

Rapid prenatal diagnosis of Facioscapulohumeral Muscular Dystrophy 1 by combined Bionano optical mapping and karyomapping

open access: yesPrenatal Diagnosis, 2019
To explore the feasibility of performing rapid prenatal diagnoses of FSHD1 using a combination of Bianano optical mapping and linkage‐based karyomapping.
Yuting Zheng   +10 more
semanticscholar   +1 more source

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