Results 31 to 40 of about 576,432 (292)
Refinement of optical map assemblies [PDF]
Bioinformatics, 2006 Abstract Motivation: Genomic mutations and variations provide insightful information about the functionality of sequence elements and their association with human diseases. Traditionally, variations are identified through analysis of short DNA sequences, usually shorter than 1000 bp per fragment. Optical maps provide both faster and more
Anton, Valouev +3 more
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Frontiers in Physiology, 2013 Alternans of action potential duration has been associated with T-wave alternans and the development of arrhythmias because it produces large gradients of repolarization. However, little is known about alternans dynamics in large mammalian hearts.
Alessio eGizzi +5 more
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Optogenetic Control of Human Induced Pluripotent Stem Cell‐Derived Cardiac Tissue Models
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Optogenetics, using light‐sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high‐resolution optogenetic approaches to modulate electrical activity in 2‐ and 3‐dimensional ...
Amit Gruber +8 more
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Multiplication and division of the orbital angular momentum of light with diffractive transformation optics [PDF]
, 2019 We present a method to efficiently multiply or divide the orbital angular momentum (OAM) of light beams using a sequence of two optical elements. The key-element is represented by an optical transformation mapping the azimuthal phase gradient of the ...
Massari, Michele +2 more
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Advances in optical mapping for genomic research
Computational and Structural Biotechnology Journal, 2020 Recent advances in optical mapping have allowed the construction of improved genome assemblies with greater contiguity. Optical mapping also enables genome comparison and identification of large-scale structural variations.
Yuxuan Yuan +2 more
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Frontiers in Physiology, 2019 IntroductionThe upstroke of optical action potentials (APs) recorded from intact hearts are generally recognized to be slower than those recorded with microelectrodes.
Christopher O’Shea +4 more
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Co-Registration of Optically Sensed Images and Correlation (COSI-Corr): an Operational Methodology for Ground Deformation Measurements [PDF]
, 2008 Recent methodological progress, Co-Registration of Optically Sensed Images and Correlation, outlined here, makes it possible to measure horizontal ground deformation from optical images on an operational basis, using the COSI-Corr software package ...
Avouac, Jean-Philippe +3 more
core +1 more source
Optical Mapping of Cardiac Electromechanics [PDF]
Biophysical Journal, 2016 Cardiac biophysics rests on three fundamental pillars: energy production, electrical excitation, and mechanical work. Studies of cardiac metabolism, bioelectricity, and biomechanics have been very productive at all levels of reduced complexity, but especially at the levels of tissue, cell, and molecule.
Matthew W, Kay, Igor R, Efimov
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Frontiers in Physiology, 2014 Light scattering during optical imaging of electrical activation within the heart is known to significantlydistort the optically-recorded action potential (AP) upstroke, as well as affecting the magnitude of the measured response of ventricular tissue to
Martin J Bishop, Gernot ePlank
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Computational methods for optical mapping [PDF]
GigaScience, 2014 Optical mapping and newer genome mapping technologies based on nicking enzymes provide low resolution but long-range genomic information. The optical mapping technique has been successfully used for assessing the quality of genome assemblies and for detecting large-scale structural variants and rearrangements that cannot be detected using current ...
Mendelowitz, Lee, Pop, Mihai
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