Results 51 to 60 of about 5,938,476 (293)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Memory Capacity of a novel optical neural net architecture [PDF]
, 1989 A new associative memory neural network which can be constructed using optical matched filters is described. It has three layers, the centre one being iterative with its weights set prior to training.
Midwinter, JE, Selviah, DR
core
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Incoherent Optical Neural Networks for Passive and Delay-Free Inference in Natural Light
PhotonicsOptical neural networks are hardware neural networks implemented based on physical optics, and they have demonstrated advantages of high speed, low energy consumption, and resistance to electromagnetic interference in the field of image processing ...
Rui Chen +3 more
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Optical implementation of the Kak neural network [PDF]
Information Sciences, 2005 We show that the Kak neural network is suitable for optical implementation using a bipolar matrix vector multiplier. We demonstrate how the CC4 algorithm, with suitable modifications to the structure and training algorithm, may be used to build an optical neural network implementing N-Parity.
Shortt, Alison +3 more
openaire +3 more sources
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Scientific Computing with Diffractive Optical Neural Networks
Advanced Intelligent Systems, 2023 Diffractive optical neural networks (DONNs) are emerging as high‐throughput and energy‐efficient hardware platforms to perform all‐optical machine learning (ML) in machine vision systems.
Ruiyang Chen +3 more
doaj +1 more source
Deferring the learning for better generalization in radial basis neural networks [PDF]
, 2001 Proceeding of: International Conference Artificial Neural Networks — ICANN 2001. Vienna, Austria, August 21–25, 2001The level of generalization of neural networks is heavily dependent on the quality of the training data.
Galván, Inés M. +5 more
core +1 more source