Results 121 to 130 of about 1,364,074 (300)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Linear and nonlinear capacitive coupling of electro-opto-mechanical photonic crystal cavities [PDF]

, 2014
We fabricate and characterize a microscale silicon electro-opto-mechanical system whose mechanical motion is coupled capacitively to an electrical circuit and optically via radiation pressure to a photonic crystal cavity.
Fink, Johannes M., Hill, Jeff T., Lei, Chan U., Painter, Oskar, Pitanti, Alessandro, Safavi-Naeini, Amir H., Tredicucci, Alessandro   +6 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Preparation of (Tb0.94−xLu0.06Hox)2O3 transparent ceramics with high Verdet constants for magneto-optical applications

Journal of Advanced Ceramics
Magneto-optical transparent ceramics exhibiting the Faraday effect provide new opportunities for optical isolator applications. In this study, magneto-optical transparent ceramics (Tb0.94−xLu0.06Hox)2O3 (x = 0, 0.005, 0.01, 0.0125, and 0.015) were ...
Yaozhi Wang, Wei Jing, Weiwei Li, Tao Xu, Jie Li, Renxin Zhang, Xilong Qin, Jian Chen, Binchu Mei   +8 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Non-Destructive Evaluation and Characterization of Transparent MgAl₂O₄ Spinel Ceramics via Moiré Interferometry

Ceramics
This work employs moiré interferometry to investigate the influence of sintering temperature and sandblasting on the optical and mechanical properties of magnesium aluminate spinel (MgAl2O4).
Rahima Meziane, Salim Benaissa, Abdelbaki Cherouana, Sofiane Bouheroum, Khadidja Hoggas, Said Meguellati, Mohamed Hamidouche, Gilbert Fantozzi   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Effect of Y substitution on the microstructure, magneto-optical, and thermal properties of (Tb1−xYx)3Al5O12 transparent ceramics

Journal of Advanced Ceramics
Faraday isolators can prevent the front-end system from disturbance and damage caused by a back-reflected beam, so they are important elements in laser systems.
Lixuan Zhang, Dianjun Hu, Xiao Li, Ziyu Liu, Chen Hu, Lexiang Wu, Tingsong Li, Dariusz Hreniak, Jiang Li   +8 more
doaj   +1 more source