Results 111 to 120 of about 1,364,074 (300)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Awareness, knowledge, and practice: A survey of glaucoma in north Indian rural residents

open access: yesIndian Journal of Ophthalmology, 2014
Background: Studies done on the prevalence of glaucoma have reported a high proportion of undiagnosed patients. Late diagnosis is related to increased risk of glaucoma associated with visual disability.
Parveen Rewri, Mukesh Kakkar
doaj   +1 more source

Design and experimental demonstration of optomechanical paddle nanocavities

open access: yes, 2015
We present the design, fabrication and initial characterization of a paddle nanocavity consisting of a suspended sub-picogram nanomechanical resonator optomechanically coupled to a photonic crystal nanocavity. The optical and mechanical properties of the
Barclay, Paul E.   +6 more
core   +1 more source

Multimodal eye's optical quality (MEOQ)

open access: yes, 2023
Within the visual system, the optics of the eye is responsible for forming images of external objects on the ocular fundus for its photo-reception and neural interpretation. However, the eye is not perfect and its capabilities may be limited by aberrations and scattering.
openaire   +6 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Comparison of objective visual quality between SMILE and FS-LASIK in moderate-to-high myopia

open access: yesFrontiers in Medicine
PurposeThis study aims to compare the changes in the corneal wavefront aberrations and the objective visual quality resulting from two types of eye surgery—small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (
Huaxian Zou   +11 more
doaj   +1 more source

Bound whispering gallery modes in circular arrays of dielectric spherical particles

open access: yes, 2006
Low-dimensional ordered arrays of optical elements can possess bound modes having an extremely high quality factor. Typically, these arrays consist of metal elements which have significantly high light absorption thus restricting performance.
A. L. Burin   +6 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Monitoring the low doping regime in graphene using Raman 2D peak-splits: Comparison of gated Raman and transport measurements [PDF]

open access: yes, 2019
Avoiding charge density fluctuations and impurities in graphene is vital for high-quality graphene-based devices. Traditional characterization methods require device fabrication and electrical transport measurements, which are labor-intensive and time ...
Barton, David   +4 more
core   +1 more source

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