Results 201 to 210 of about 4,520 (260)

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Ciliary flow and morphology shape mass transport at the surface and within gastrovascular cavities of black corals. [PDF]

Commun Biol
Godefroid M, Otero-Ferrer F, Wind-Hansen M, Behrendt L, Ransquin I, Soler-Onís E, Espino F, Littmann S, Ahmerkamp S.   +8 more
europepmc   +1 more source

SAT1‐Induced Spermidine Depletion Potentiates Food Allergy

Advanced Science, EarlyView.
Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu, Beiyu Zhang, Junjuan Wang, Yue Jiang, Shiwen Han, Qianwei Wang, Lingyu Zeng, Jinfeng Wang, Huilian Che   +8 more
wiley   +1 more source

Quantum coherent manipulation and readout of superconducting vortex states. [PDF]

Nature
Nambisan A, Günzler S, Rieger D, Gosling N, Geisert S, Carpentier V, Zapata N, Field M, Milošević MV, Lopez CAD, Padurariu C, Kubala B, Ankerhold J, Wernsdorfer W, Spiecker M, Pop IM.   +15 more
europepmc   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Surface relief formation with light possessing multiple vortices. [PDF]

Nanophotonics
Zhao J, Kizaki K, Taguchi A, Ono M, Hirayama S, Hirayama S, Omatsu T.   +6 more
europepmc   +1 more source

Vectorial lasing with designable topological charges based on Möbius-like correspondence in quasi-BICs. [PDF]

Light Sci Appl
Wang X, Wu Z, Wang J, Shi L, Zi J.
europepmc   +1 more source

Optical Vortex Harmonic Generation Enabled by Confinement-Induced Photonic Spin-Orbit Coupling. [PDF]

Nano Lett
Ha CK, Kim EM, Moon KJ, Kang MS.
europepmc   +1 more source