Results 91 to 100 of about 1,199,811 (345)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal, Dario B. Rodrigues, Weiguang Yao, Jason K. Molitoris, Matthew E. Witek, Shifeng Chen   +5 more
wiley   +1 more source

Optical transmission theory for metal-insulator-metal periodic nanostructures

Nanophotonics, 2016
A semi-analytical formalism for the optical properties of a metal-insulator-metal periodic nanostructure using coupled-mode theory is presented. This structure consists in a dielectric layer in between two metallic layers with periodic one-dimensional ...
Blanchard-Dionne Andre-Pierre, Meunier Michel   +1 more
doaj   +1 more source

Marsilio Ficino's Allegorical Reading of Optical Phenomena

Teorie vědy, 2020
As a Platonist, Marsilio Ficino (1433–1499) was deeply interested in light  and its qualities. As a matter of fact, the metaphysics of light is so fundamental for him that it appears, treated more or less systematically, almost in all of his works.
Martin Žemla
doaj   +1 more source

Plasma‐activated media selectively induces apoptotic death via an orchestrated oxidative stress pathway in high‐grade serous ovarian cancer cells

Molecular Oncology, EarlyView.
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies, Raja Ganesen, John Toubia, Sung‐Ha Hong, Sushil Kumar KC, Martin K. Oehler, Carmela Ricciardelli, Endre J. Szili, Nirmal Robinson, Melissa R. Pitman   +9 more
wiley   +1 more source

Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling, Timothy D. Keiper, Daniela Branco, Grace Gwe‐Ya Kim, Kevin L Moore, Xenia Ray   +5 more
wiley   +1 more source

Adaptive Optics for Astronomy

, 2012
Adaptive Optics is a prime example of how progress in observational astronomy can be driven by technological developments. At many observatories it is now considered to be part of a standard instrumentation suite, enabling ground-based telescopes to ...
Arsenault R, Beuzit J-L, Bonaccini Calia D, Davies R, Ellerbroek BL, Ellerbroek BL, Foy R, Frogel J, Gendron E, Hubin N, Jones T, Labeyrie A, Markus Kasper, Merkle F, Merline WJ, Neichel B, Richard Davies, Riffel R, Rigaut F, Rousset G, Tyson RK, Wild V, Wizinowich P   +22 more
core   +1 more source

Low-Power All-Optical Switch Based on Time-Reversed Microring Laser

IEEE Photonics Journal, 2012
An all-optical switch based on an absorbing microring resonator laterally coupled to two waveguides is described theoretically using the coupling of modes in time formalism and numerically using the finite-difference time-domain method.
Adam Mock
doaj   +1 more source

Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework

Molecular Oncology, EarlyView.
This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto, Hege Marie Vedeld, Guro Elisabeth Lind, Marine Jeanmougin   +3 more
wiley   +1 more source

Statistical process control to monitor use of a web‐based autoplanning tool

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens, Raphael Douglas, Mary Gronberg, Kelly Nealon, Joy Zhang, Laurence Court   +5 more
wiley   +1 more source