Results 91 to 100 of about 1,235,699 (372)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Automatic optical inspection of microscale defects on curved surfaces

open access: yesNihon Kikai Gakkai ronbunshu
In many areas of manufacturing, there is a growing need for imaging technology that non-destructively inspects the surface of products. However, detecting micro-defects on curved surfaces is challenging because the appropriate imaging conditions can vary
Hiroya KANO, Hiroshi OHNO, Hideaki OKANO
doaj   +1 more source

Three-Dimensional Chirped High-Contrast Grating Hollow-Core Waveguide

open access: yesIEEE Photonics Journal, 2012
A 3-D chirped high-contrast grating hollow-core waveguide (HCG-HW) exhibits highly efficient 2-D (transverse and lateral) light confinement. Compared with step-index ones, laterally chirped HCG-HWs (graded index) can pronouncedly reduce the propagation ...
Yang Yue   +10 more
doaj   +1 more source

The Influence of Structure Parameters on Nanoantennas’ Optical Response

open access: yesChemosensors, 2020
Currently, huge opportunities for the inclusion of new optical devices in our lives have been appearing. There are evident and irrefutable examples for nanoantenna applications. They can be used to improve already developed devices or even be used as the
Ricardo A. Marques Lameirinhas   +2 more
doaj   +1 more source

Optical realization of the dissipative quantum oscillator

open access: yes, 2016
An optical realization of the damped quantum oscillator, based on transverse light dynamics in an optical resonator with slowly-moving mirrors, is theoretically suggested.
Eaton, Shane M., Longhi, Stefano
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

James Short and John Harrison: personal genius and public knowledge

open access: yesScience Museum Group Journal, 2014
The instrument maker James Short, whose output was exclusively reflecting telescopes, was a sustained and consistent supporter of the clock and watch maker John Harrison.
Professor Jim Bennett
doaj   +1 more source

Glider-Based Active Acoustic Monitoring of Currents and Turbidity in the Coastal Zone

open access: yesRemote Sensing, 2020
The recent integration of Acoustic Doppler Current Profilers (ADCPs) onto underwater gliders changes the way current and sediment dynamics in the coastal zone can be monitored.
Mathieu Gentil   +7 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A Scalable, Self-Analyzing Digital Locking System for use on Quantum Optics Experiments

open access: yes, 2011
Digital control of optics experiments has many advantages over analog control systems, specifically in terms of scalability, cost, flexibility, and the integration of system information into one location.
B. C. Buchler   +6 more
core   +1 more source

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