Results 41 to 50 of about 12,436,371 (298)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Optimal control in models with conductive‐radiative heat transfer
In this paper an optimal control problem for the elliptic boundary value problem with nonlocal boundary conditions is considered. It is shown that the weak solutions of the boundary value problem depend smoothly on the control parameter and that the cost
K. Birgelis
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Optimal Boundary-Flux Control of a Sharp Moving Interface in the Classical Two-Phase Stefan Problem
In this paper, we study the optimal boundary control of solidification governed by the classical two-phase Stefan problem with a sharp moving interface.
Khalid Ali Alanezy, Jihad Souissi
doaj +1 more source
Explicit solutions for distributed, boundary and distributed-boundary elliptic optimal control problems [PDF]
31 pages, 2 figures Accepted in Journal of Applied Mathematics and ...
Julieta Bollati +2 more
openaire +3 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The purpose of this paper is to study the solvability of the quaternary continuous classical boundary optimal control vector problem dominated by quaternary nonlinear parabolic boundary value problem with state constraints.
Jamil A. Ali Al-Hawasy, Fetan J. Naji
doaj +1 more source
Linear-Quadratic Optimal Control for Boundary Controlled Networks of Waves
Linear-Quadratic optimal controls are computed for a class of boundary controlled, boundary observed hyperbolic infinite-dimensional systems, which may be viewed as networks of waves. The main results of this manuscript consist in converting the infinite-dimensional continuous-time systems into infinite-dimensional discrete-time systems for which the ...
Anthony Hastir, Birgit Jacob, Hans Zwart
openaire +4 more sources

