Results 61 to 70 of about 12,436,371 (298)

Optimal Control of Aeroacoustic Flows: Transpiration Boundary Control [PDF]

open access: yes3rd Theoretical Fluid Mechanics Meeting, 2002
We consider the optimal boundary control of aeroacoustic noise governed by the two-dimensional unsteady compressible Euler equations. The control is the time and space varying wall-normal velocity (transpiration velocity) on a subset of a solid wall. The objective functional to be minimized is a measure of acoustic amplitude.
Samuel Collis   +2 more
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A shape-measure method for solving free-boundary elliptic systems with boundary control function [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization, 2013
This article deals with a computational algorithmic approach for obtaining the optimal solution of a general free boundary problem governed by an elliptic equation with boundary control and functional criterion. After determining the weak solution of the
A. Fakharzadeh Jahromi
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Optimal control of non-stationary differential linear repetitive processes

open access: yes, 2008
Differential repetitive processes are a distinct class of continuous discrete 2D linear systems of both systems theoretic and applications interest. The feature which makes them distinct from other classes of such systems is the fact that information ...
Rogers, E   +7 more
core   +2 more sources

ON EXISTENCE OF BOUNDED FEASIBLE SOLUTIONS TO NEUMANN BOUNDARY CONTROL PROBLEM FOR p-LAPLACE EQUATION WITH EXPONENTIAL TYPE OF NONLINEARITY

open access: yesJournal of Optimization, Differential Equations and Their Applications, 2018
We study an optimal control problem for mixed Dirichlet-Neumann boundary value problem for the strongly non-linear elliptic equation with p-Laplace operator and L1-nonlinearity in its right-hand side. A distribution u acting on a part of boundary of open
Peter I. Kogut   +2 more
doaj   +1 more source

Time optimal problems with boundary controls

open access: yesDifferential and Integral Equations, 2000
The authors consider the control system \[ \begin{aligned}{\partial y(t, x) \over \partial t} + Ay(t, x) + f(t, x, y(t, x)) &= 0 \quad (0 \leq t \leq T, \;x \in \Omega) \\ {\partial y(t, x) \over \partial n_A} + g(t, x, y(t, x), v(t, x)) &= 0 \quad(0 \leq t \leq T, \;x \in \Gamma)\end{aligned} \] in an \(m\)-dimensional domain \(\Omega\) with boundary \
Raymond, J. P., Zidani, H.
openaire   +3 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Construction of asymptotically optimal control for crisscross network from a free boundary problem

open access: yesStochastic Systems, 2016
An asymptotic framework for optimal control of multiclass stochastic processing networks, using formal diffusion approximations under suitable temporal and spatial scaling, by Brownian control problems (BCP) and their equivalent workload formulations ...
Amarjit Budhiraja   +2 more
doaj   +1 more source

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