Results 51 to 60 of about 111,028 (264)

A shape-measure method for solving free-boundary elliptic systems with boundary control function [PDF]

Iranian Journal of Numerical Analysis and Optimization, 2013
This article deals with a computational algorithmic approach for obtaining the optimal solution of a general free boundary problem governed by an elliptic equation with boundary control and functional criterion. After determining the weak solution of the
A. Fakharzadeh Jahromi
doaj   +1 more source

Optimal Control of Aeroacoustic Flows: Transpiration Boundary Control [PDF]

3rd Theoretical Fluid Mechanics Meeting, 2002
We consider the optimal boundary control of aeroacoustic noise governed by the two-dimensional unsteady compressible Euler equations. The control is the time and space varying wall-normal velocity (transpiration velocity) on a subset of a solid wall. The objective functional to be minimized is a measure of acoustic amplitude.
Samuel Collis, Kaveh Ghayour, Matthias Heinkenschloss   +2 more
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

ON EXISTENCE OF BOUNDED FEASIBLE SOLUTIONS TO NEUMANN BOUNDARY CONTROL PROBLEM FOR p-LAPLACE EQUATION WITH EXPONENTIAL TYPE OF NONLINEARITY

Journal of Optimization, Differential Equations and Their Applications, 2018
We study an optimal control problem for mixed Dirichlet-Neumann boundary value problem for the strongly non-linear elliptic equation with p-Laplace operator and L1-nonlinearity in its right-hand side. A distribution u acting on a part of boundary of open
Peter I. Kogut, Rosanna Manzo, Mykola V. Poliakov   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Construction of asymptotically optimal control for crisscross network from a free boundary problem

Stochastic Systems, 2016
An asymptotic framework for optimal control of multiclass stochastic processing networks, using formal diffusion approximations under suitable temporal and spatial scaling, by Brownian control problems (BCP) and their equivalent workload formulations ...
Amarjit Budhiraja, Xin Liu, Subhamay Saha   +2 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimal Control-Based Inverse Determination of Electrode Distribution for Electroosmotic Micromixer

Micromachines, 2017
This paper presents an optimal control-based inverse method used to determine the distribution of the electrodes for the electroosmotic micromixers with external driven flow from the inlet.
Yuan Ji, Yongbo Deng, Zhenyu Liu, Teng Zhou, Yihui Wu, Shizhi Qian   +5 more
doaj   +1 more source

Time optimal problems with boundary controls

Differential and Integral Equations, 2000
The authors consider the control system \[ \begin{aligned}{\partial y(t, x) \over \partial t} + Ay(t, x) + f(t, x, y(t, x)) &= 0 \quad (0 \leq t \leq T, \;x \in \Omega) \\ {\partial y(t, x) \over \partial n_A} + g(t, x, y(t, x), v(t, x)) &= 0 \quad(0 \leq t \leq T, \;x \in \Gamma)\end{aligned} \] in an \(m\)-dimensional domain \(\Omega\) with boundary \
Raymond, J. P., Zidani, H.
openaire   +3 more sources