Results 81 to 90 of about 12,436,371 (298)
Optimality Conditions for Parabolic Stochastic Optimal Control Problems with Boundary Controls
Applied Mathematics & OptimizationThe author studies the optimality conditions for a class of control problems driven by a cylindrical Wiener process, and expresses them by a stochastic maximum principle in differential form. The problem is to minimize the cost functional of the type \[ J(x,u)=\mathbb{E}\int_{0}^{T}f(t,x(t),u(t))dt+\mathbb{E}(h(x(T)), \] subject to the stochastic ...
openaire +2 more sources
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Optimal control problems for impulsive systems with integral boundary conditions
Electronic Journal of Differential Equations, 2013 In this article, the optimal control problem is considered when the state of the system is described by the impulsive differential equations with integral boundary conditions.
Allaberen Ashyralyev, Yagub A. Sharifov
doaj
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
On optimal control problem for the heat equation with integral boundary condition
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016 In this paper we consider the optimal control problem for the heat equation with an integral boundary condition. Control functions are the free term and the coefficient of the equation of state and the free term of the integral boundary condition.
Rafiq K Tagiev, Vahab M Habibov
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A priori error estimates for optimal control problems with pointwise constraints on the gradient of the state [PDF]
, 2011 We analyze a finite element approximation of an elliptic optimal control problem with pointwise bounds on the gradient of the state variable. We derive convergence rates if the control space is discretized implicitly by the state equation. In contrast to
Ortner, Christoph +4 more
core +1 more source
Pontryagin’s Maximum Principle for the Optimal Control Problems with Multipoint Boundary Conditions
Abstract and Applied Analysis, 2015 Optimal control problem with multipoint boundary conditions is considered. Sufficient conditions for the existence and uniqueness of the solution of boundary value problem for every fixed admissible control are obtained. First order increment formula for
M. J. Mardanov, Y. A. Sharifov
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Equilibrium Points for Optimal Investment with Vintage Capital [PDF]
The paper concerns the study of equilibrium points, namely the stationary solutions to the closed loop equation, of an infinite dimensional and infinite horizon boundary control problem for linear partial differential equations. Sufficient conditions for
Silvia Faggian
core