Results 91 to 100 of about 764,565 (289)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Optimal Binary Locally Repairable Codes via Anticodes
, 2015 This paper presents a construction for several families of optimal binary locally repairable codes (LRCs) with small locality (2 and 3). This construction is based on various anticodes.
Silberstein, Natalia, Zeh, Alexander
core +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Low‐complexity near‐optimal detection of dc2‐balanced codes
Electronics Letters, 2016 Two constructions of a low‐complexity near‐optimal detection method of dc2‐balanced codes are presented. The methods presented are improvements on Slepian's algorithm for optimal detection of permutation codes.
K.A.S. Immink
doaj +1 more source
Real-Coded Chemical Reaction Optimization
IEEE Transactions on Evolutionary Computation, 2012 Optimization problems can generally be classified as continuous and discrete, based on the nature of the solution space. A recently developed chemical-reaction-inspired metaheuristic, called chemical reaction optimization (CRO), has been shown to perform well in many optimization problems in the discrete domain.
Lam, AYS, Yu, JJQ, Li, VOK
openaire +3 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
علوم رایانش و فناوری اطلاعات, 2021 All binary codes, even Huffman optimal code, are kind of non-optimal bit arrangement. Therefore, binary code optimization is a challenging problem. In this paper an algorithm is proposed to optimize the codes by converting any type of binary code to a ...
پرویز قره باقری +2 more
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Hardness of decoding quantum stabilizer codes [PDF]
, 2013 In this article we address the computational hardness of optimally decoding a quantum stabilizer code. Much like classical linear codes, errors are detected by measuring certain check operators which yield an error syndrome, and the decoding problem ...
Iyer, Pavithran, Poulin, David
core