Results 101 to 110 of about 3,285,258 (314)

Optimal Entrainment of Heterogeneous Noisy Neurons

Frontiers in Neuroscience, 2015
We develop a methodology to design a stimulus optimized to entrain nonlinear, noisy limit cycle oscillators with uncertain properties. Conditions are derived which guarantee that the stimulus will entrain the oscillators despite these uncertainties ...
Dan eWilson, Abbey B Holt, Theoden I Netoff, Jeff eMoehlis   +3 more
doaj   +1 more source

Optimal control theory : a method for the design of wind instruments [PDF]

, 2010
It has been asserted previously by the author that optimal control theory can be a valuable framework for theoretical studies about the shape that a wind instrument should have in order to satisfy some optimization criterion, inside a fairly general ...
Vey, Georges Le
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Optimal Control of Endemic Epidemic Diseases With Behavioral Response

IEEE Open Journal of Control Systems
Behavioral factors play a crucial role in the emergence, spread, and containment of human diseases, significantly influencing the effectiveness of intervention measures.
Francesco Parino, Lorenzo Zino, Alessandro Rizzo   +2 more
doaj   +1 more source

Entropy Generation Rate Minimization for Methanol Synthesis via a CO₂ Hydrogenation Reactor

Entropy, 2019
The methanol synthesis via CO2 hydrogenation (MSCH) reaction is a useful CO2 utilization strategy, and this synthesis path has also been widely applied commercially for many years.
Penglei Li, Lingen Chen, Shaojun Xia, Lei Zhang   +3 more
doaj   +1 more source

Optimal control theory for inflation targeting [PDF]

We make a case for the usefulness of an optimal control approach for the central banks' choice of interest rates in inflation target regimes. We illustrate it with data from selected developed and emerging countries with longest experience of inflation ...
Roberto Meurer, Sergio Da Silva, Thiago Veloso   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Inflation targeting and optimal control theory [PDF]

We make a case for the usefulness of an optimal control approach for the central banks’ choice of interest rates in inflation target regimes. We illustrate with data from selected developed and emerging countries with longest experience of inflation ...
Da Silva, Sergio, Meurer, Roberto, Veloso, Thiago   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Analysis of fractional order model on higher institution students' anxiety towards mathematics with optimal control theory. [PDF]

Sci Rep, 2023
Teklu SW.
europepmc   +1 more source