Results 101 to 110 of about 19,271,700 (291)

Application of fractional optimal control theory for the mitigating of novel coronavirus in Algeria. [PDF]

Results Phys, 2022
El Hadj Moussa Y, Boudaoui A, Ullah S, Muzammil K, Riaz MB.   +4 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

An optimal control theory approach for freight structure path evolution post-COVID-19 pandemic. [PDF]

Socioecon Plann Sci, 2023
Lu C, Ye Y, Fang Y, Fang J.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Mathematical modeling analysis on the dynamics of university students animosity towards mathematics with optimal control theory. [PDF]

Sci Rep, 2022
Teklu SW, Terefe BB.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

An optimal-control based integrated model of supply chain [PDF]

Problems of supply chain scheduling are challenged by high complexity, combination of continuous and discrete processes, integrated production and transportation operations as well as dynamics and resulting requirements for adaptability and stability ...
Ivanov, Dmitry
core  

A minmax problem for parabolic systems with competitive interactions

Electronic Journal of Differential Equations, 1999
In this paper we model the evolution and interaction between two competing populations as a system of parabolic partial differential equations. The interaction between the two populations is quantified by the presence of non-local terms in the system of ...
Sanjay Chawla
doaj  

An efficient model‐free adaptive optimal control of continuous‐time nonlinear non‐zero‐sum games based on integral reinforcement learning with exploration

IET Control Theory & Applications
To reduce the learning time and space occupation, this study presents a novel model‐free algorithm for obtaining the Nash equilibrium solution of continuous‐time nonlinear non‐zero‐sum games.
Lei Guo, Wenbo Xiong, Yuan Song, Dongming Gan   +3 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source