Results 51 to 60 of about 3,285,258 (314)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Correction: A control theory approach to optimal pandemic mitigation.

open access: yesPLoS ONE
[This corrects the article DOI: 10.1371/journal.pone.0247445.].
Prakhar Godara   +2 more
doaj   +2 more sources

Adaptive Online Data-Driven Tracking Control for Highly Flexible Aircrafts With Partial Observability

open access: yesIEEE Access, 2020
In this study, an adaptive online data-driven tracking controller for a highly flexible aircraft (HFA) was developed. This control design innovatively combines integral reinforcement learning (IRL) and the optimal control theory to ensure asymptotic ...
Chi Peng, Jianjun Ma
doaj   +1 more source

Fractional conservation laws in optimal control theory

open access: yes, 2007
Using the recent formulation of Noether's theorem for the problems of the calculus of variations with fractional derivatives, the Lagrange multiplier technique, and the fractional Euler-Lagrange equations, we prove a Noether-like theorem to the more ...
D. Baleanu   +30 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Optimal navigation of microswimmers in complex and noisy environments

open access: yesNew Journal of Physics, 2022
We design new navigation strategies for travel time optimization of microscopic self-propelled particles in complex and noisy environments. In contrast to strategies relying on the results of optimal control theory or machine learning approaches ...
Lorenzo Piro   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Noosphere as Optimal Control. Part 1. Control Theory, Geosphere and Biosphere [PDF]

open access: yesФилософия и космология, 2017
The conceptual system developed in optimal control theory for technical purposes is used as a philosophical instrument applied to cyclic information processes, which are expected to be the basis of noosphere.
Boris Balter, Marina Faminskaya
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Second-law-like inequalities with information and their interpretations

open access: yesNew Journal of Physics, 2014
In a thermodynamic process with measurement and feedback, the second law of thermodynamics is no longer valid. In its place, various second-law-like inequalities have been advanced that each incorporate a distinct additional term accounting for the ...
Jordan M Horowitz, Henrik Sandberg
doaj   +1 more source

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