Results 91 to 100 of about 2,095,520 (306)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Optimal emission tax with endogenous location choice of duopolistic firms [PDF]

This paper explores optimal environmental tax policy under which duopoly firms strategically choose the location of their plants in a simple three-stage game.
Jun-ichi Itaya, Makoto Okamura, Masako Ikefuji   +2 more
core   +3 more sources

Fertilizer Logistics in Brazil: Application of a Mixed-Integer Programming Mathematical Model for Optimal Mixer Locations

Logistics
Background: Brazil is one of the largest consumers of fertilizers and is highly dependent on the international market to meet its demand for agricultural production inputs.
Fernando Pauli de Bastiani, Thiago Guilherme Péra, José Vicente Caixeta-Filho   +2 more
doaj   +1 more source

Cost Sensitivity Analysis on the Optimal Location of Technology Providers In Kentucky [PDF]

A warehouse location model was utilized in order to expand upon previous research. The aim was to more accurately depicting the optimal location for an agribusiness firm providing precision agriculture technologies in the state of Kentucky.
Dillon, Carl R., Saghaian, Sayed H., Shockley, Jordan M.   +2 more
core   +1 more source

On Quantizer Design for Distributed Bayesian Estimation in Sensor Networks

, 2014
We consider the problem of distributed estimation under the Bayesian criterion and explore the design of optimal quantizers in such a system. We show that, for a conditionally unbiased and efficient estimator at the fusion center and when local ...
Chen, Biao, He, Hao, Varshney, Pramod K., Vempaty, Aditya   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Policy design and the optimal location of forests in Flanders [PDF]

This paper analyses the current Flemish afforestation policy and shows that this policy is likely to be non-optimal and can be improved. An important step in improving the afforestation policy in Flanders is the selection of the optimal location of a ...
Ellen Moons, Sandra Rousseau
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Simulated Annealing for Location Area Planning in Cellular networks

, 2010
LA planning in cellular network is useful for minimizing location management cost in GSM network. In fact, size of LA can be optimized to create a balance between the LA update rate and expected paging rate within LA.
Agravat, R. R., Hasan, M. I., Prajapati, N. B.   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source